1. Home
  2. Analysis
  3. Habitrol
  4. Irritability

Habitrol and Irritability - a phase IV clinical study of FDA data

Summary:

Irritability is reported as a side effect among people who take Habitrol (nicotine), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Thrive, and have Quit smoking.

The phase IV clinical study analyzes which people have Irritability when taking Habitrol. It is created by eHealthMe based on reports of 5,545 people who have side effects when taking Habitrol from the FDA, and is updated regularly.

What is Habitrol?

Habitrol has active ingredients of nicotine. eHealthMe is studying from 5,553 Habitrol users. Check the latest studies of Habitrol.

What is Irritability?

Irritability is found to be associated with 1,697 drugs and 2,459 conditions by eHealthMe. Check the latest studies of Irritability.

On Jul, 27, 2026

5,545 people reported to have side effects when taking Habitrol.
Among them, 53 people (0.96%) have Irritability.

Could Habitrol cause Irritability?

Among these 53 people:

How long have people been on Habitrol when they have Irritability? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Irritability when taking Habitrol? *

  • female: 60 %
  • male: 40 %

What is the age of people who have Irritability when taking Habitrol? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 9.09 %
  • 30-39: 3.03 %
  • 40-49: 12.12 %
  • 50-59: 54.55 %
  • 60+: 21.21 %

What are other drugs people take besides Habitrol? *

  1. Thrive: 3 people, 5.66%
  2. Morphine: 2 people, 3.77%
  3. Zoloft: 1 person, 1.89%
  4. Nicoderm Cq: 1 person, 1.89%
  5. Amlodipine: 1 person, 1.89%
  6. Ativan: 1 person, 1.89%
  7. Biotin: 1 person, 1.89%
  8. Cardizem: 1 person, 1.89%
  9. Demerol: 1 person, 1.89%
  10. Hydroxyzine: 1 person, 1.89%

What are other side effects people have besides Irritability? *

  1. Nicotine Dependence: 13 people, 24.53%
  2. Stress And Anxiety: 13 people, 24.53%
  3. Insomnia (sleeplessness): 10 people, 18.87%
  4. Abnormal Dreams: 7 people, 13.21%
  5. Suicidal Ideation: 6 people, 11.32%
  6. Aggression: 6 people, 11.32%
  7. Nausea (feeling of having an urge to vomit): 6 people, 11.32%
  8. Depression: 5 people, 9.43%
  9. Headache (pain in head): 5 people, 9.43%
  10. Nervousness: 5 people, 9.43%

What are the existing conditions these people have? *

  1. Quit Smoking: 43 people, 81.13%
  2. Stress And Anxiety: 2 people, 3.77%
  3. Sleep Disorder: 1 person, 1.89%
  4. High Blood Pressure: 1 person, 1.89%
  5. High Blood Cholesterol: 1 person, 1.89%
  6. Heart Rate Increased: 1 person, 1.89%
  7. Depression: 1 person, 1.89%
  8. Abdominal Discomfort: 1 person, 1.89%

* Approximation only. Some reports may have incomplete information.

Do you take Habitrol and have Irritability?

- Check whether Irritability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Habitrol:

Irritability treatments and more:

How severe was Irritability and when was it recovered:

Expand to all the drugs that have ingredients of nicotine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Habitrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Irritability:

Browse all the conditions that are associated with Irritability:

How the study uses the data?

The study uses data from the FDA. It is based on nicotine (the active ingredients of Habitrol) and Habitrol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.