Hc and Nervousness - a phase IV clinical study of FDA data

Summary:

Nervousness is reported as a side effect among people who take Hc (hydrocortisone), especially for people who are male, 40-49 old, have been taking the drug for 6 - 12 months also take Invokana, and have Neuroendocrine carcinoma.

The phase IV clinical study analyzes which people have Nervousness when taking Hc. It is created by eHealthMe based on reports of 1,263 people who have side effects when taking Hc from the FDA, and is updated regularly.

What is Hc?

Hc has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 1,369 Hc users. Check the latest studies of Hc.

What is Nervousness?

Nervousness is found to be associated with 1,659 drugs and 1,892 conditions by eHealthMe. Check the latest studies of Nervousness.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

1,263 people reported to have side effects when taking Hc.
Among them, 11 people (0.87%) have Nervousness.

Could Hc cause Nervousness?

Among these 11 people:

How long have people been on Hc when they have Nervousness? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Nervousness when taking Hc? *

  • female: 18.18 %
  • male: 81.82 %

What is the age of people who have Nervousness when taking Hc? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 88.89 %
  • 50-59: 11.11 %
  • 60+: 0.0 %

What are other drugs people take besides Hc? *

  1. Sandostatin: 8 people, 72.73%
  2. Kombiglyze Xr: 8 people, 72.73%
  3. Invokana: 8 people, 72.73%
  4. Buscopan: 4 people, 36.36%
  5. Varenicline Tartrate: 2 people, 18.18%
  6. Metoclopramide Hydrochloride: 2 people, 18.18%
  7. Kenalog: 1 person, 9.09%
  8. Flexeril: 1 person, 9.09%
  9. Digoxin: 1 person, 9.09%
  10. Diovan: 1 person, 9.09%

What are other side effects people have besides Nervousness? *

  1. Stress And Anxiety: 10 people, 90.91%
  2. Pain: 9 people, 81.82%
  3. Fatigue (feeling of tiredness): 9 people, 81.82%
  4. Dry Mouth: 9 people, 81.82%
  5. High Blood Pressure: 9 people, 81.82%
  6. Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 8 people, 72.73%
  7. Glycosylated Haemoglobin Increased: 8 people, 72.73%
  8. Eye Pain: 8 people, 72.73%
  9. Hepatic Vein Thrombosis (obstruction in the veins of the liver caused by a blood clot): 8 people, 72.73%
  10. Diarrhea: 8 people, 72.73%

What are the existing conditions these people have? *

  1. Neuroendocrine Carcinoma (cancer tumour that arise from cells of the endocrine (hormonal) and nervous systems): 8 people, 72.73%
  2. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 9.09%
  3. Overgrowth Bacterial (extra growth due to bacteria): 1 person, 9.09%
  4. Nausea And Vomiting: 1 person, 9.09%
  5. Nausea (feeling of having an urge to vomit): 1 person, 9.09%
  6. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 9.09%
  7. Mouth Ulcers: 1 person, 9.09%
  8. Hypersensitivity: 1 person, 9.09%
  9. Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 1 person, 9.09%
  10. Contrast Media Allergy (reaction associated with the use of intravenous contrast material during radiology): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Hc and have Nervousness?

- Check whether Nervousness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hc:

  • Hc (1,369 reports)

Nervousness treatments and more:

How severe was Nervousness and when was it recovered:

Expand to all the drugs that have ingredients of hydrocortisone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nervousness:

Browse all the conditions that are associated with Nervousness:


How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone (the active ingredients of Hc) and Hc (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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