Hctz and Bleeding into the skin - a phase IV clinical study of FDA data

Summary:

Bleeding into the skin is reported as a side effect among people who take Hctz (hydrochlorothiazide), especially for people who are female, 60+ old, also take Celebrex, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Bleeding into the skin when taking Hctz. It is created by eHealthMe based on reports of 23,493 people who have side effects when taking Hctz from the FDA, and is updated regularly.

What is Hctz?

Hctz has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 24,823 Hctz users. Check the latest studies of Hctz.

What is Bleeding into the skin?

Bleeding into the skin is found to be associated with 937 drugs and 1,908 conditions by eHealthMe. Check the latest studies of Bleeding into the skin.

On Apr, 09, 2026

23,493 people reported to have side effects when taking Hctz.
Among them, 49 people (0.21%) have Bleeding into the skin.

Could Hctz cause Bleeding into the skin?

Among these 49 people:

What is the gender of people who have Bleeding into the skin when taking Hctz? *

female: 83.72 %
male: 16.28 %

What is the age of people who have Bleeding into the skin when taking Hctz? *

What are other drugs people take besides Hctz? *

What are other side effects people have besides Bleeding into the skin? *

Fatigue (feeling of tiredness): 32 people, 65.31%
Joint Pain: 26 people, 53.06%
Rashes (redness): 24 people, 48.98%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 22 people, 44.90%
Oedema Peripheral (superficial swelling): 21 people, 42.86%
Nausea (feeling of having an urge to vomit): 21 people, 42.86%
Limb Discomfort (discomfort in leg): 20 people, 40.82%
Drug Ineffective: 20 people, 40.82%
Drug Intolerance (drug sensitivity): 20 people, 40.82%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 20 people, 40.82%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 20 people, 40.82%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 8 people, 16.33%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 7 people, 14.29%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 7 people, 14.29%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 8.16%
Muscle Disorder (muscle disease): 4 people, 8.16%
Nausea (feeling of having an urge to vomit): 3 people, 6.12%
Multiple Myeloma (cancer of the plasma cells): 3 people, 6.12%
Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 2 people, 4.08%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 4.08%

* Approximation only. Some reports may have incomplete information.

Do you take Hctz and have Bleeding into the skin?

- Check whether Bleeding into the skin is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hctz:

Hctz (24,823 reports)

Browse all side effects of Hctz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bleeding into the skin:

Bleeding into the skin (937 drugs)

Browse all the conditions that are associated with Bleeding into the skin:

Bleeding into the skin (1,908 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide (the active ingredients of Hctz) and Hctz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.