Hctz and Muscle twitching - a phase IV clinical study of FDA data

Summary:

Muscle twitching is reported as a side effect among people who take Hctz (hydrochlorothiazide), especially for people who are female, 60+ old, also take Pantoprazole, and have Fibromyalgia.

The phase IV clinical study analyzes which people have Muscle twitching when taking Hctz. It is created by eHealthMe based on reports of 23,493 people who have side effects when taking Hctz from the FDA, and is updated regularly.

What is Hctz?

Hctz has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 24,823 Hctz users. Check the latest studies of Hctz.

What is Muscle twitching?

Muscle twitching is found to be associated with 1,240 drugs and 1,905 conditions by eHealthMe. Check the latest studies of Muscle twitching.

On Jul, 12, 2026

23,493 people reported to have side effects when taking Hctz.
Among them, 38 people (0.16%) have Muscle twitching.

Among these 38 people:

What is the gender of people who have Muscle twitching when taking Hctz? *

female: 78.12 %
male: 21.88 %

What is the age of people who have Muscle twitching when taking Hctz? *

What are other drugs people take besides Hctz? *

What are other side effects people have besides Muscle twitching? *

Tremor (trembling or shaking movements in one or more parts of your body): 19 people, 50.00%
Dizziness: 15 people, 39.47%
Migraine (headache): 13 people, 34.21%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 12 people, 31.58%
Muscle Spasms (muscle contraction): 10 people, 26.32%
Weight Increased: 6 people, 15.79%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 6 people, 15.79%
Nasopharyngitis (inflammation of the nasopharynx): 5 people, 13.16%
Dysgraphia (impaired ability to learn to write): 5 people, 13.16%
Skin Blushing/flushing (a sudden reddening of the face, neck): 5 people, 13.16%

What are the existing conditions these people have? *

Fibromyalgia (a long-term condition which causes pain all over the body): 12 people, 31.58%
Abdominal Pain: 11 people, 28.95%
High Blood Cholesterol: 4 people, 10.53%
Stress And Anxiety: 3 people, 7.89%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 7.89%
Pain: 2 people, 5.26%
Depression: 2 people, 5.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.26%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.26%
Post-Traumatic Stress Disorder: 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Hctz and have Muscle twitching?

- Check whether Muscle twitching is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hctz:

Hctz (24,823 reports)

Muscle twitching treatments and more:

Muscle twitching (29,030 reports)

Browse all side effects of Hctz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle twitching:

Muscle twitching (1,240 drugs)

Browse all the conditions that are associated with Muscle twitching:

Muscle twitching (1,905 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide (the active ingredients of Hctz) and Hctz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.