Hctz and Osteomyelitis - a phase IV clinical study of FDA data

Summary:

Osteomyelitis is reported as a side effect among people who take Hctz (hydrochlorothiazide), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Metformin, and have Narcolepsy.

The phase IV clinical study analyzes which people have Osteomyelitis when taking Hctz. It is created by eHealthMe based on reports of 23,493 people who have side effects when taking Hctz from the FDA, and is updated regularly.

What is Hctz?

Hctz has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 24,823 Hctz users. Check the latest studies of Hctz.

What is Osteomyelitis?

Osteomyelitis (infection of bone) is found to be associated with 1,426 drugs and 1,327 conditions by eHealthMe. Check the latest studies of Osteomyelitis.



On Jul, 18, 2026

23,493 people reported to have side effects when taking Hctz.
Among them, 18 people (0.08%) have Osteomyelitis.

Could Hctz cause Osteomyelitis?

Among these 18 people:

How long have people been on Hctz when they have Osteomyelitis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 100 %
  • 10+ years: 0.0 %

What is the gender of people who have Osteomyelitis when taking Hctz? *

  • female: 77.78 %
  • male: 22.22 %

What is the age of people who have Osteomyelitis when taking Hctz? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 50 %
  • 60+: 50 %

What are other drugs people take besides Hctz? *

  1. Metformin: 6 people, 33.33%
  2. Neurontin: 5 people, 27.78%
  3. Ultram: 5 people, 27.78%
  4. Lidoderm: 5 people, 27.78%
  5. Imitrex: 4 people, 22.22%
  6. Restasis: 4 people, 22.22%
  7. Xyrem: 4 people, 22.22%
  8. Oxycontin: 4 people, 22.22%
  9. Lasix: 4 people, 22.22%
  10. Levemir: 3 people, 16.67%

What are other side effects people have besides Osteomyelitis? *

  1. Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 27.78%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 22.22%
  3. Pain: 4 people, 22.22%
  4. Osteopenia (a condition where bone mineral density is lower than normal): 4 people, 22.22%
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 22.22%
  6. Migraine (headache): 4 people, 22.22%
  7. Hypotension (abnormally low blood pressure): 3 people, 16.67%
  8. Weakness: 3 people, 16.67%
  9. Therapeutic Response Decreased (less preventive response): 3 people, 16.67%
  10. Gastric Ulcer (stomach ulcer): 3 people, 16.67%

What are the existing conditions these people have? *

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 22.22%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 22.22%
  3. Diabetes: 3 people, 16.67%
  4. High Blood Cholesterol: 3 people, 16.67%
  5. Type 2 Diabetes: 3 people, 16.67%
  6. Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 2 people, 11.11%
  7. Hypotension (abnormally low blood pressure): 1 person, 5.56%
  8. Diabetic Eye Disease: 1 person, 5.56%
  9. Diabetic Foot: 1 person, 5.56%
  10. Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Hctz and have Osteomyelitis?

- Check whether Osteomyelitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hctz:

  • Hctz (24,823 reports)

Osteomyelitis treatments and more:

How severe was Osteomyelitis and when was it recovered:

Expand to all the drugs that have ingredients of hydrochlorothiazide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hctz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteomyelitis:

Browse all the conditions that are associated with Osteomyelitis:


How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide (the active ingredients of Hctz) and Hctz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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