Hepsera and Heart attack - a phase IV clinical study of FDA data

Summary:

Heart attack is reported as a side effect among people who take Hepsera (adefovir dipivoxil), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Gaviscon, and have Hepatic neoplasm malignant.

The phase IV clinical study analyzes which people have Heart attack when taking Hepsera. It is created by eHealthMe based on reports of 3,102 people who have side effects when taking Hepsera from the FDA, and is updated regularly.

What is Hepsera?

Hepsera has active ingredients of adefovir dipivoxil. It is often used in hepatitis b. eHealthMe is studying from 3,113 Hepsera users. Check the latest studies of Hepsera.

What is Heart attack?

Heart attack is found to be associated with 2,481 drugs and 3,296 conditions by eHealthMe. Check the latest studies of Heart attack.



On Jul, 17, 2026

3,102 people reported to have side effects when taking Hepsera.
Among them, 13 people (0.42%) have Heart attack.

Could Hepsera cause Heart attack?

Among these 13 people:

How long have people been on Hepsera when they have Heart attack? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 25 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 25 %
  • 10+ years: 0.0 %

What is the gender of people who have Heart attack when taking Hepsera? *

  • female: 61.54 %
  • male: 38.46 %

What is the age of people who have Heart attack when taking Hepsera? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 36.36 %
  • 60+: 63.64 %

What are other drugs people take besides Hepsera? *

  1. Advil: 3 people, 23.08%
  2. Gaviscon: 3 people, 23.08%
  3. Lansoprazole: 2 people, 15.38%
  4. Cyclosporine: 2 people, 15.38%
  5. Epivir: 2 people, 15.38%
  6. Nexavar: 2 people, 15.38%
  7. Lipitor: 1 person, 7.69%
  8. Lasix: 1 person, 7.69%
  9. Indapamide: 1 person, 7.69%
  10. Plavix: 1 person, 7.69%

What are other side effects people have besides Heart attack? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 30.77%
  2. Bradycardia (abnormally slow heart action): 4 people, 30.77%
  3. Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 23.08%
  4. Cytolytic Hepatitis (dissolution or destruction of a liver cell): 3 people, 23.08%
  5. High Blood Cholesterol: 3 people, 23.08%
  6. Hypertriglyceridaemia (excess of triglycerides in the blood): 3 people, 23.08%
  7. Ischaemic Stroke (stroke; caused by an interruption in the flow of blood to the brain): 3 people, 23.08%
  8. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 2 people, 15.38%
  9. Stable Angina (a constant chest pain): 2 people, 15.38%
  10. Oesophageal Varices Haemorrhage (bleeding from extremely dilated sub-mucosal veins in the lower third of the oesophagus): 2 people, 15.38%

What are the existing conditions these people have? *

  1. Hepatic Neoplasm Malignant (liver cancer): 2 people, 15.38%
  2. Transaminases Increased: 1 person, 7.69%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.69%
  4. Headache (pain in head): 1 person, 7.69%
  5. Diabetes: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Hepsera and have Heart attack?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hepsera:

Heart attack treatments and more:

How severe was Heart attack and when was it recovered:

Expand to all the drugs that have ingredients of adefovir dipivoxil:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hepsera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart attack:

Browse all the conditions that are associated with Heart attack:


How the study uses the data?

The study uses data from the FDA. It is based on adefovir dipivoxil (the active ingredients of Hepsera) and Hepsera (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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