Humira and Cerebral calcification - a phase IV clinical study of FDA data

Summary:

Cerebral calcification is reported as a side effect among people who take Humira (adalimumab), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Methotrexate, and have Ankylosing spondylitis.

The phase IV clinical study analyzes which people have Cerebral calcification when taking Humira. It is created by eHealthMe based on reports of 758,421 people who have side effects when taking Humira from the FDA, and is updated regularly.

What is Humira?

Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 761,396 Humira users. Check the latest studies of Humira.

What is Cerebral calcification?

Cerebral calcification (abnormal deposits of calcium in certain areas of the brain) is found to be associated with 56 drugs and 208 conditions by eHealthMe. Check the latest studies of Cerebral calcification.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

758,421 people reported to have side effects when taking Humira.
Among them, 15 people (0.0%) have Cerebral calcification.

Could Humira cause Cerebral calcification?

Among these 15 people:

How long have people been on Humira when they have Cerebral calcification? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 33.33 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 16.67 %
  • 5 - 10 years: 16.67 %
  • 10+ years: 0.0 %

What is the gender of people who have Cerebral calcification when taking Humira? *

  • female: 73.33 %
  • male: 26.67 %

What is the age of people who have Cerebral calcification when taking Humira? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 16.67 %
  • 50-59: 33.33 %
  • 60+: 50.0 %

What are other drugs people take besides Humira? *

  1. Methotrexate: 4 people, 26.67%
  2. Actemra: 2 people, 13.33%
  3. Simponi: 2 people, 13.33%
  4. Remicade: 2 people, 13.33%
  5. Orencia: 2 people, 13.33%
  6. Gabapentin: 1 person, 6.67%
  7. Arava: 1 person, 6.67%
  8. Bentyl: 1 person, 6.67%
  9. Calcium: 1 person, 6.67%
  10. Crestor: 1 person, 6.67%

What are other side effects people have besides Cerebral calcification? *

  1. Head Injury: 3 people, 20.00%
  2. Brain Neoplasm (tumour of brain): 3 people, 20.00%
  3. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 3 people, 20.00%
  4. Fall: 3 people, 20.00%
  5. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 20.00%
  6. Pain: 3 people, 20.00%
  7. Bedridden: 2 people, 13.33%
  8. Psoriasis (immune-mediated disease that affects the skin): 2 people, 13.33%
  9. Interstitial Lung Disease: 2 people, 13.33%
  10. Head Discomfort: 2 people, 13.33%

What are the existing conditions these people have? *

  1. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 20.00%
  2. High Blood Pressure: 3 people, 20.00%
  3. Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 20.00%
  4. Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 20.00%
  5. Psoriasis (immune-mediated disease that affects the skin): 2 people, 13.33%
  6. Gastritis (inflammation of stomach): 2 people, 13.33%
  7. Thyroid Diseases: 1 person, 6.67%
  8. Muscle Aches (muscle pain): 1 person, 6.67%
  9. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 1 person, 6.67%
  10. High Blood Cholesterol: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Humira and have Cerebral calcification?

- Check whether Cerebral calcification is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Humira:

Cerebral calcification treatments and more:

How severe was Cerebral calcification and when was it recovered:

Expand to all the drugs that have ingredients of adalimumab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Humira:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cerebral calcification:

Browse all the conditions that are associated with Cerebral calcification:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on adalimumab (the active ingredients of Humira) and Humira (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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