Hydrea and Concomitant disease aggravated - a phase IV clinical study of FDA data

Summary:

Concomitant disease aggravated is reported as a side effect among people who take Hydrea (hydroxyurea), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Famotidine, and have Primary myelofibrosis.

The phase IV clinical study analyzes which people have Concomitant disease aggravated when taking Hydrea. It is created by eHealthMe based on reports of 8,922 people who have side effects when taking Hydrea from the FDA, and is updated regularly.

What is Hydrea?

Hydrea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 9,083 Hydrea users. Check the latest studies of Hydrea.

What is Concomitant disease aggravated?

Concomitant disease aggravated (advanced due to some of accompanying) is found to be associated with 596 drugs and 631 conditions by eHealthMe. Check the latest studies of Concomitant disease aggravated.

On Aug, 06, 2026

8,922 people reported to have side effects when taking Hydrea.
Among them, 33 people (0.37%) have Concomitant disease aggravated.

Could Hydrea cause Concomitant disease aggravated?

Among these 33 people:

How long have people been on Hydrea when they have Concomitant disease aggravated? *

What is the gender of people who have Concomitant disease aggravated when taking Hydrea? *

female: 33.33 %
male: 66.67 %

What is the age of people who have Concomitant disease aggravated when taking Hydrea? *

What are other drugs people take besides Hydrea? *

What are other side effects people have besides Concomitant disease aggravated? *

Anaemia (lack of blood): 11 people, 33.33%
Primary Myelofibrosis (primary disorder of the bone marrow): 11 people, 33.33%
Thrombocytopenia (decrease of platelets in blood): 10 people, 30.30%
White Blood Cell Count Increased: 9 people, 27.27%
Pneumonia: 7 people, 21.21%
Cardiac Failure Congestive: 7 people, 21.21%
Fever: 7 people, 21.21%
Hepatic Function Abnormal: 7 people, 21.21%
Oxygen Saturation Decreased: 7 people, 21.21%
Malaise (a feeling of general discomfort or uneasiness): 6 people, 18.18%

What are the existing conditions these people have? *

Primary Myelofibrosis (primary disorder of the bone marrow): 14 people, 42.42%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 8 people, 24.24%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 7 people, 21.21%
High Blood Pressure: 3 people, 9.09%
Leukaemia (blood or bone marrow cancer): 2 people, 6.06%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.06%
Cardiac Failure Congestive: 2 people, 6.06%
Nephrogenic Anaemia (anaemia due to kidney disease): 2 people, 6.06%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 6.06%
Splenomegaly (enlargement of spleen): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrea and have Concomitant disease aggravated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrea:

Hydrea (9,083 reports)

Browse all side effects of Hydrea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Concomitant disease aggravated:

Concomitant disease aggravated (596 drugs)

Browse all the conditions that are associated with Concomitant disease aggravated:

Concomitant disease aggravated (631 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea (the active ingredients of Hydrea) and Hydrea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.