Hydrea and Deep venous thrombosis - a phase IV clinical study of FDA data

Summary:

Deep venous thrombosis is reported as a side effect among people who take Hydrea (hydroxyurea), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Jakafi, and have Primary myelofibrosis.

The phase IV clinical study analyzes which people have Deep venous thrombosis when taking Hydrea. It is created by eHealthMe based on reports of 8,922 people who have side effects when taking Hydrea from the FDA, and is updated regularly.

What is Hydrea?

Hydrea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 9,083 Hydrea users. Check the latest studies of Hydrea.

What is Deep venous thrombosis?

Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis) is found to be associated with 2,064 drugs and 2,967 conditions by eHealthMe. Check the latest studies of Deep venous thrombosis.

On Aug, 09, 2026

8,922 people reported to have side effects when taking Hydrea.
Among them, 45 people (0.5%) have Deep venous thrombosis.

Could Hydrea cause Deep venous thrombosis?

Among these 45 people:

How long have people been on Hydrea when they have Deep venous thrombosis? *

What is the gender of people who have Deep venous thrombosis when taking Hydrea? *

female: 32.43 %
male: 67.57 %

What is the age of people who have Deep venous thrombosis when taking Hydrea? *

What are other drugs people take besides Hydrea? *

What are other side effects people have besides Deep venous thrombosis? *

Pulmonary Embolism (blockage of the main artery of the lung): 18 people, 40.00%
Anaemia (lack of blood): 12 people, 26.67%
Headache (pain in head): 11 people, 24.44%
High Blood Pressure: 8 people, 17.78%
Platelet Count Increased: 8 people, 17.78%
White Blood Cell Count Increased: 7 people, 15.56%
Thrombocytopenia (decrease of platelets in blood): 7 people, 15.56%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 6 people, 13.33%
Oedema Peripheral (superficial swelling): 6 people, 13.33%
Dizziness: 6 people, 13.33%

What are the existing conditions these people have? *

Primary Myelofibrosis (primary disorder of the bone marrow): 11 people, 24.44%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 6 people, 13.33%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 8.89%
Blood Potassium Decreased: 4 people, 8.89%
Chest Pain: 4 people, 8.89%
Glaucoma (increased fluid pressure in the eye with vision loss): 4 people, 8.89%
High Blood Pressure: 4 people, 8.89%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 8.89%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 8.89%
Bone Marrow Disorder: 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrea and have Deep venous thrombosis?

- Check whether Deep venous thrombosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrea:

Hydrea (9,083 reports)

Browse all side effects of Hydrea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Deep venous thrombosis:

Deep venous thrombosis (2,064 drugs)

Browse all the conditions that are associated with Deep venous thrombosis:

Deep venous thrombosis (2,967 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea (the active ingredients of Hydrea) and Hydrea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.