Hydrocodone and Angina pectoris aggravated - a phase IV clinical study of FDA data

Summary:

Angina pectoris aggravated is reported as a side effect among people who take Hydrocodone (hydrocodone bitartrate; ibuprofen), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Morphine, and have High blood pressure.

The phase IV clinical study analyzes which people have Angina pectoris aggravated when taking Hydrocodone. It is created by eHealthMe based on reports of 13,053 people who have side effects when taking Hydrocodone from the FDA, and is updated regularly.

What is Hydrocodone?

Hydrocodone has active ingredients of hydrocodone bitartrate; ibuprofen. eHealthMe is studying from 13,115 Hydrocodone users. Check the latest studies of Hydrocodone.

What is Angina pectoris aggravated?

Angina pectoris aggravated (chest pain due to ischemia of the heart muscle) is found to be associated with 1,381 drugs and 650 conditions by eHealthMe. Check the latest studies of Angina pectoris aggravated.

On Jul, 18, 2026

13,053 people reported to have side effects when taking Hydrocodone.
Among them, 16 people (0.12%) have Angina pectoris aggravated.

Could Hydrocodone cause Angina pectoris aggravated?

Among these 16 people:

How long have people been on Hydrocodone when they have Angina pectoris aggravated? *

What is the gender of people who have Angina pectoris aggravated when taking Hydrocodone? *

female: 21.43 %
male: 78.57 %

What is the age of people who have Angina pectoris aggravated when taking Hydrocodone? *

What are other drugs people take besides Hydrocodone? *

What are other side effects people have besides Angina pectoris aggravated? *

Weakness: 9 people, 56.25%
Nausea And Vomiting: 7 people, 43.75%
Fatigue (feeling of tiredness): 7 people, 43.75%
Nausea (feeling of having an urge to vomit): 7 people, 43.75%
Cough: 6 people, 37.50%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 6 people, 37.50%
High Blood Cholesterol: 6 people, 37.50%
Itching: 5 people, 31.25%
Back Pain: 5 people, 31.25%
High Blood Pressure: 5 people, 31.25%

What are the existing conditions these people have? *

Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 2 people, 12.50%
Nausea (feeling of having an urge to vomit): 2 people, 12.50%
Libido Disorder (a sexual dysfunction relating to loss of sexual desire): 2 people, 12.50%
High Blood Pressure: 2 people, 12.50%
Type 2 Diabetes: 1 person, 6.25%
Immunodeficiency Disorders: 1 person, 6.25%
Cardiac Failure Chronic: 1 person, 6.25%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 6.25%
Gastritis (inflammation of stomach): 1 person, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocodone and have Angina pectoris aggravated?

- Check whether Angina pectoris aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrocodone:

Hydrocodone (13,115 reports)

Angina pectoris aggravated treatments and more:

Angina pectoris aggravated (393 reports)

How severe was Angina pectoris aggravated and when was it recovered:

Angina pectoris aggravated in Hydrocodone

Expand to all the drugs that have ingredients of hydrocodone bitartrate; ibuprofen:

Angina pectoris aggravated and drugs with ingredients of hydrocodone bitartrate; ibuprofen

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrocodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Angina pectoris aggravated:

Angina pectoris aggravated (1,381 drugs)

Browse all the conditions that are associated with Angina pectoris aggravated:

Angina pectoris aggravated (650 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocodone bitartrate; ibuprofen (the active ingredients of Hydrocodone) and Hydrocodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.