Hydrocortisone and Muscle twitching - a phase IV clinical study of FDA data

Summary:

Muscle twitching is reported as a side effect among people who take Hydrocortisone (hydrocortisone), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Acetaminophen, and have Headache.

The phase IV clinical study analyzes which people have Muscle twitching when taking Hydrocortisone. It is created by eHealthMe based on reports of 39,960 people who have side effects when taking Hydrocortisone from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Muscle twitching?

Muscle twitching is found to be associated with 1,239 drugs and 1,905 conditions by eHealthMe. Check the latest studies of Muscle twitching.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

39,960 people reported to have side effects when taking Hydrocortisone.
Among them, 87 people (0.22%) have Muscle twitching.

Could Hydrocortisone cause Muscle twitching?

Among these 87 people:

How long have people been on Hydrocortisone when they have Muscle twitching? *

What is the gender of people who have Muscle twitching when taking Hydrocortisone? *

female: 70.13 %
male: 29.87 %

What is the age of people who have Muscle twitching when taking Hydrocortisone? *

What are other drugs people take besides Hydrocortisone? *

Acetaminophen: 42 people, 48.28%
Lansoprazole: 36 people, 41.38%
Ibuprofen: 35 people, 40.23%
Amoxicillin: 35 people, 40.23%
Metoclopramide: 33 people, 37.93%
Keppra: 32 people, 36.78%
Fluconazole: 31 people, 35.63%
Chlorpheniramine Maleate: 31 people, 35.63%
Exemestane: 29 people, 33.33%
Spironolactone: 29 people, 33.33%

What are other side effects people have besides Muscle twitching? *

Fatigue (feeling of tiredness): 46 people, 52.87%
Muscle Spasms (muscle contraction): 41 people, 47.13%
Constipation: 39 people, 44.83%
Headache (pain in head): 38 people, 43.68%
Rashes (redness): 36 people, 41.38%
Chest Pain: 36 people, 41.38%
Dizziness: 35 people, 40.23%
Hair Loss: 33 people, 37.93%
Nausea (feeling of having an urge to vomit): 32 people, 36.78%
Vaginal Discharge: 32 people, 36.78%

What are the existing conditions these people have? *

Headache (pain in head): 30 people, 34.48%
Wheezing (a high-pitched whistling sound made while you breath): 29 people, 33.33%
Breast Cancer: 29 people, 33.33%
Diarrhea: 29 people, 33.33%
Cough: 28 people, 32.18%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 28 people, 32.18%
Oropharyngeal Pain: 28 people, 32.18%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 28 people, 32.18%
Muscle Spasms (muscle contraction): 28 people, 32.18%
Constipation: 28 people, 32.18%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortisone and have Muscle twitching?

- Check whether Muscle twitching is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrocortisone:

Hydrocortisone (40,425 reports)

Muscle twitching treatments and more:

Muscle twitching (29,030 reports)

Browse all side effects of Hydrocortisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle twitching:

Muscle twitching (1,239 drugs)

Browse all the conditions that are associated with Muscle twitching:

Muscle twitching (1,905 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone (the active ingredients of Hydrocortisone) and Hydrocortisone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.