Hydrocortisone and Scratch - a phase IV clinical study of FDA data

Summary:

Scratch is reported as a side effect among people who take Hydrocortisone (hydrocortisone), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Acetaminophen, and have Crohn's disease.

The phase IV clinical study analyzes which people have Scratch when taking Hydrocortisone. It is created by eHealthMe based on reports of 39,960 people who have side effects when taking Hydrocortisone from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Scratch?

Scratch is found to be associated with 688 drugs and 749 conditions by eHealthMe. Check the latest studies of Scratch.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

39,960 people reported to have side effects when taking Hydrocortisone.
Among them, 44 people (0.11%) have Scratch.

Among these 44 people:

How long have people been on Hydrocortisone when they have Scratch? *

What is the gender of people who have Scratch when taking Hydrocortisone? *

female: 70 %
male: 30 %

What is the age of people who have Scratch when taking Hydrocortisone? *

What are other drugs people take besides Hydrocortisone? *

Acetaminophen: 17 people, 38.64%
Prednisone: 16 people, 36.36%
Inflectra: 14 people, 31.82%
Benadryl: 12 people, 27.27%
Calcium: 9 people, 20.45%
Pantoprazole Sodium: 8 people, 18.18%
Dupixent: 7 people, 15.91%
Triamcinolone Acetonide: 6 people, 13.64%
Xolair: 5 people, 11.36%
Desonide: 5 people, 11.36%

What are other side effects people have besides Scratch? *

Itching: 19 people, 43.18%
Drug Ineffective: 15 people, 34.09%
Urinary Tract Infection: 15 people, 34.09%
Rashes (redness): 13 people, 29.55%
Fatigue (feeling of tiredness): 12 people, 27.27%
Skin Plaque (red, scaly patches to appear on the skin): 11 people, 25.00%
Fall: 11 people, 25.00%
Back Pain: 10 people, 22.73%
Intestinal Obstruction: 10 people, 22.73%
Pain: 9 people, 20.45%

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 19 people, 43.18%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 7 people, 15.91%
Psoriasis (immune-mediated disease that affects the skin): 5 people, 11.36%
Polymyalgia Rheumatica (pain in many muscles): 3 people, 6.82%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 4.55%
Renal Cancer Metastatic (cancer of kidney spreads to other part): 2 people, 4.55%
Renal Cell Carcinoma (a kidney cancer): 2 people, 4.55%
Migraine (headache): 1 person, 2.27%
Cardiac Failure Congestive: 1 person, 2.27%
Flatulence (flatus expelled through the anus): 1 person, 2.27%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortisone and have Scratch?

- Check whether Scratch is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrocortisone:

Hydrocortisone (40,425 reports)

Scratch treatments and more:

Scratch (10,633 reports)

Browse all side effects of Hydrocortisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Scratch:

Scratch (688 drugs)

Browse all the conditions that are associated with Scratch:

Scratch (749 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone (the active ingredients of Hydrocortisone) and Hydrocortisone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.