Hydrocortone and Hyperkalemia - a phase IV clinical study of FDA data

Summary:

Hyperkalemia is reported as a side effect among people who take Hydrocortone (hydrocortisone acetate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Vidaza, and have Myelodysplastic syndrome.

The phase IV clinical study analyzes which people have Hyperkalemia when taking Hydrocortone. It is created by eHealthMe based on reports of 785 people who have side effects when taking Hydrocortone from the FDA, and is updated regularly.

What is Hydrocortone?

Hydrocortone has active ingredients of hydrocortisone acetate. It is often used in pain. eHealthMe is studying from 912 Hydrocortone users. Check the latest studies of Hydrocortone.

What is Hyperkalemia?

Hyperkalemia (damage to or disease of the kidney) is found to be associated with 1,953 drugs and 2,940 conditions by eHealthMe. Check the latest studies of Hyperkalemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

785 people reported to have side effects when taking Hydrocortone.
Among them, 15 people (1.91%) have Hyperkalemia.

Among these 15 people:

How long have people been on Hydrocortone when they have Hyperkalemia? *

What is the gender of people who have Hyperkalemia when taking Hydrocortone? *

female: 46.67 %
male: 53.33 %

What is the age of people who have Hyperkalemia when taking Hydrocortone? *

What are other drugs people take besides Hydrocortone? *

What are other side effects people have besides Hyperkalemia? *

Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 5 people, 33.33%
Urinary Tract Infection: 5 people, 33.33%
Upper Respiratory Tract Inflammation: 5 people, 33.33%
Pneumonia: 5 people, 33.33%
Renal Impairment (severely reduced kidney function): 5 people, 33.33%
Thrombocytopenia (decrease of platelets in blood): 5 people, 33.33%
Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 20.00%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 20.00%
Cardiac Failure: 3 people, 20.00%
Constipation: 3 people, 20.00%

What are the existing conditions these people have? *

Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 6 people, 40.00%
Osteoporosis (bones weak and more likely to break): 3 people, 20.00%
High Blood Pressure: 3 people, 20.00%
Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 20.00%
Cardiac Failure: 3 people, 20.00%
Breast Cancer: 3 people, 20.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 20.00%
Multiple Myeloma (cancer of the plasma cells): 2 people, 13.33%
Adverse Event: 2 people, 13.33%
Adrenal Cortical Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroid hormones): 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortone and have Hyperkalemia?

- Check whether Hyperkalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrocortone:

Hydrocortone (912 reports)

Hyperkalemia treatments and more:

Hyperkalemia (78,085 reports)

Browse all side effects of Hydrocortone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperkalemia:

Hyperkalemia (1,953 drugs)

Browse all the conditions that are associated with Hyperkalemia:

Hyperkalemia (2,940 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone acetate (the active ingredients of Hydrocortone) and Hydrocortone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.