Hydrocortone and Multi-organ failure - a phase IV clinical study of FDA data

Summary:

Multi-organ failure is reported as a side effect among people who take Hydrocortone (hydrocortisone acetate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Vancomycin, and have Pneumonia aspiration.

The phase IV clinical study analyzes which people have Multi-organ failure when taking Hydrocortone. It is created by eHealthMe based on reports of 785 people who have side effects when taking Hydrocortone from the FDA, and is updated regularly.

What is Hydrocortone?

Hydrocortone has active ingredients of hydrocortisone acetate. It is often used in pain. eHealthMe is studying from 912 Hydrocortone users. Check the latest studies of Hydrocortone.

What is Multi-organ failure?

Multi-organ failure (multisystem organ failure) is found to be associated with 1,393 drugs and 2,279 conditions by eHealthMe. Check the latest studies of Multi-organ failure.



On Jul, 16, 2026

785 people reported to have side effects when taking Hydrocortone.
Among them, 24 people (3.06%) have Multi-organ failure.

Could Hydrocortone cause Multi-organ failure?

Among these 24 people:

How long have people been on Hydrocortone when they have Multi-organ failure? *

  • < 1 month: 80 %
  • 1 - 6 months: 20 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Multi-organ failure when taking Hydrocortone? *

  • female: 37.5 %
  • male: 62.5 %

What is the age of people who have Multi-organ failure when taking Hydrocortone? *

  • 0-1: 0.0 %
  • 2-9: 4.55 %
  • 10-19: 0.0 %
  • 20-29: 27.27 %
  • 30-39: 0.0 %
  • 40-49: 18.18 %
  • 50-59: 18.18 %
  • 60+: 31.82 %

What are other drugs people take besides Hydrocortone? *

  1. Vancomycin: 9 people, 37.50%
  2. Acetaminophen: 7 people, 29.17%
  3. Fluconazole: 7 people, 29.17%
  4. Lasix: 6 people, 25.00%
  5. Dobutrex: 6 people, 25.00%
  6. Etoposide: 6 people, 25.00%
  7. Ambien: 5 people, 20.83%
  8. Fentanyl: 5 people, 20.83%
  9. Morphine: 5 people, 20.83%
  10. Metoclopramide: 5 people, 20.83%

What are other side effects people have besides Multi-organ failure? *

  1. Septic Shock (shock due to blood infection): 11 people, 45.83%
  2. Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 9 people, 37.50%
  3. Erythema Multiforme (a type of hypersensitivity reaction): 7 people, 29.17%
  4. Acute Kidney Failure: 6 people, 25.00%
  5. Fever: 6 people, 25.00%
  6. Abdominal Compartment Syndrome (increased pressure in abdomen): 5 people, 20.83%
  7. Bacterial Infection: 5 people, 20.83%
  8. White Blood Cell Count Increased: 5 people, 20.83%
  9. Hypotension (abnormally low blood pressure): 5 people, 20.83%
  10. Pneumonia: 5 people, 20.83%

What are the existing conditions these people have? *

  1. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 4 people, 16.67%
  2. Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 4 people, 16.67%
  3. Urine Output Decreased: 3 people, 12.50%
  4. Inflammation: 3 people, 12.50%
  5. Arrhythmias (irregular heartbeat): 3 people, 12.50%
  6. Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 2 people, 8.33%
  7. Infection: 2 people, 8.33%
  8. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 8.33%
  9. Pneumonia Staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus): 2 people, 8.33%
  10. Neutropenic Sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortone and have Multi-organ failure?

- Check whether Multi-organ failure is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrocortone:

Multi-organ failure treatments and more:

How severe was Multi-organ failure and when was it recovered:

Expand to all the drugs that have ingredients of hydrocortisone acetate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrocortone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multi-organ failure:

Browse all the conditions that are associated with Multi-organ failure:


How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone acetate (the active ingredients of Hydrocortone) and Hydrocortone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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