Hydroxyurea and Glaucoma - a phase IV clinical study of FDA data

Summary:

Glaucoma is reported as a side effect among people who take Hydroxyurea (hydroxyurea), especially for people who are female, 60+ old, also take Norvasc, and have High blood pressure.

The phase IV clinical study analyzes which people have Glaucoma when taking Hydroxyurea. It is created by eHealthMe based on reports of 16,937 people who have side effects when taking Hydroxyurea from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,238 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Glaucoma?

Glaucoma (increased fluid pressure in the eye with vision loss) is found to be associated with 1,245 drugs and 1,646 conditions by eHealthMe. Check the latest studies of Glaucoma.

On Apr, 28, 2026

16,937 people reported to have side effects when taking Hydroxyurea.
Among them, 29 people (0.17%) have Glaucoma.

Among these 29 people:

What is the gender of people who have Glaucoma when taking Hydroxyurea? *

female: 69.57 %
male: 30.43 %

What is the age of people who have Glaucoma when taking Hydroxyurea? *

What are other drugs people take besides Hydroxyurea? *

What are other side effects people have besides Glaucoma? *

Anaemia (lack of blood): 17 people, 58.62%
Thrombocytosis: 16 people, 55.17%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 14 people, 48.28%
Weight Decreased: 14 people, 48.28%
High Blood Pressure: 14 people, 48.28%
Osteoporosis (bones weak and more likely to break): 14 people, 48.28%
Diarrhea: 14 people, 48.28%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 13 people, 44.83%
Fatigue (feeling of tiredness): 13 people, 44.83%
Depression: 13 people, 44.83%

What are the existing conditions these people have? *

High Blood Pressure: 18 people, 62.07%
Pain: 13 people, 44.83%
Depression: 13 people, 44.83%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 12 people, 41.38%
Hyperkalemia (damage to or disease of the kidney): 4 people, 13.79%
Peripheral Arterial Occlusive Disease (reproducible ischemic muscle pain): 3 people, 10.34%
Primary Myelofibrosis (primary disorder of the bone marrow): 2 people, 6.90%
Polycythaemia (proportion of blood volume that is occupied by red blood cells increases): 2 people, 6.90%
Osteoporosis (bones weak and more likely to break): 2 people, 6.90%
Diabetes: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyurea and have Glaucoma?

- Check whether Glaucoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyurea:

Hydroxyurea (17,238 reports)

Glaucoma treatments and more:

Glaucoma (61,924 reports)

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Glaucoma:

Glaucoma (1,245 drugs)

Browse all the conditions that are associated with Glaucoma:

Glaucoma (1,646 conditions)

Related publications that referenced our studies

Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea (the active ingredients of Hydroxyurea) and Hydroxyurea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.