Hydroxyurea and Hypertriglyceridaemia - a phase IV clinical study of FDA data

Summary:

Hypertriglyceridaemia is reported as a side effect among people who take Hydroxyurea (hydroxyurea), especially for people who are male, 40-49 old, have been taking the drug for 5 - 10 years also take Jakafi, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Hypertriglyceridaemia when taking Hydroxyurea. It is created by eHealthMe based on reports of 16,937 people who have side effects when taking Hydroxyurea from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Hypertriglyceridaemia?

Hypertriglyceridaemia (excess of triglycerides in the blood) is found to be associated with 755 drugs and 763 conditions by eHealthMe. Check the latest studies of Hypertriglyceridaemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

16,937 people reported to have side effects when taking Hydroxyurea.
Among them, 35 people (0.21%) have Hypertriglyceridaemia.

Could Hydroxyurea cause Hypertriglyceridaemia?

Among these 35 people:

How long have people been on Hydroxyurea when they have Hypertriglyceridaemia? *

What is the gender of people who have Hypertriglyceridaemia when taking Hydroxyurea? *

female: 12 %
male: 88 %

What is the age of people who have Hypertriglyceridaemia when taking Hydroxyurea? *

What are other drugs people take besides Hydroxyurea? *

What are other side effects people have besides Hypertriglyceridaemia? *

High Blood Cholesterol: 20 people, 57.14%
Fatigue (feeling of tiredness): 15 people, 42.86%
Cough: 14 people, 40.00%
Depression: 14 people, 40.00%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 14 people, 40.00%
High Blood Pressure: 14 people, 40.00%
Productive Cough: 14 people, 40.00%
Red Blood Cell Count Decreased: 14 people, 40.00%
Panic Disorder: 14 people, 40.00%
Blood Count Abnormal: 14 people, 40.00%

What are the existing conditions these people have? *

Libido Disorder (a sexual dysfunction relating to loss of sexual desire): 3 people, 8.57%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 8.57%
Acute Lymphocytic Leukaemia Recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent): 2 people, 5.71%
White Blood Cell Count Increased: 1 person, 2.86%
Thrombocytosis: 1 person, 2.86%
Malignant Neoplasm Progression (cancer tumour came back): 1 person, 2.86%
Leukocytosis (increased white blood cells): 1 person, 2.86%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 1 person, 2.86%
Hiv Infection: 1 person, 2.86%
High Blood Pressure: 1 person, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyurea and have Hypertriglyceridaemia?

- Check whether Hypertriglyceridaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyurea:

Hydroxyurea (17,240 reports)

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertriglyceridaemia:

Hypertriglyceridaemia (755 drugs)

Browse all the conditions that are associated with Hypertriglyceridaemia:

Hypertriglyceridaemia (763 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea (the active ingredients of Hydroxyurea) and Hydroxyurea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.