Hydroxyurea and Intestinal obstruction - a phase IV clinical study of FDA data

Summary:

Intestinal obstruction is reported as a side effect among people who take Hydroxyurea (hydroxyurea), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Fosamax, and have Crohn's disease.

The phase IV clinical study analyzes which people have Intestinal obstruction when taking Hydroxyurea. It is created by eHealthMe based on reports of 16,937 people who have side effects when taking Hydroxyurea from the FDA, and is updated regularly.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.

What is Intestinal obstruction?

Intestinal obstruction is found to be associated with 1,884 drugs and 2,619 conditions by eHealthMe. Check the latest studies of Intestinal obstruction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 17, 2026

16,937 people reported to have side effects when taking Hydroxyurea.
Among them, 53 people (0.31%) have Intestinal obstruction.

Could Hydroxyurea cause Intestinal obstruction?

Among these 53 people:

How long have people been on Hydroxyurea when they have Intestinal obstruction? *

What is the gender of people who have Intestinal obstruction when taking Hydroxyurea? *

female: 69.39 %
male: 30.61 %

What is the age of people who have Intestinal obstruction when taking Hydroxyurea? *

What are other drugs people take besides Hydroxyurea? *

What are other side effects people have besides Intestinal obstruction? *

Haemoglobin Decreased: 9 people, 16.98%
Ascites (accumulation of fluid in the abdominal cavity): 8 people, 15.09%
Fatigue (feeling of tiredness): 7 people, 13.21%
Pneumonia: 7 people, 13.21%
Malaise (a feeling of general discomfort or uneasiness): 7 people, 13.21%
Pancreatitis (inflammation of pancreas): 6 people, 11.32%
Gallstones (stone formation by bile component): 6 people, 11.32%
Swallowing Difficulty: 6 people, 11.32%
Dehydration (dryness resulting from the removal of water): 6 people, 11.32%
Weakness: 6 people, 11.32%

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 17 people, 32.08%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 6 people, 11.32%
Pain: 5 people, 9.43%
Iron Overload: 4 people, 7.55%
Primary Myelofibrosis (primary disorder of the bone marrow): 3 people, 5.66%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 3.77%
Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 2 people, 3.77%
High Blood Pressure: 1 person, 1.89%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 1 person, 1.89%
Arterial Occlusive Disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked): 1 person, 1.89%

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyurea and have Intestinal obstruction?

- Check whether Intestinal obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyurea:

Hydroxyurea (17,240 reports)

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intestinal obstruction:

Intestinal obstruction (1,884 drugs)

Browse all the conditions that are associated with Intestinal obstruction:

Intestinal obstruction (2,619 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea (the active ingredients of Hydroxyurea) and Hydroxyurea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.