Hydroxyzine and Itchiness - a phase IV clinical study of FDA data

Summary:

Itchiness is reported as a side effect among people who take Hydroxyzine (hydroxyzine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Dupixent, and have Dermatitis atopic.

The phase IV clinical study analyzes which people have Itchiness when taking Hydroxyzine. It is created by eHealthMe based on reports of 51,890 people who have side effects when taking Hydroxyzine from the FDA, and is updated regularly.

What is Hydroxyzine?

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 54,060 Hydroxyzine users. Check the latest studies of Hydroxyzine.

What is Itchiness?

Itchiness is found to be associated with 3,379 drugs and 4,515 conditions by eHealthMe. Check the latest studies of Itchiness.

On Dec, 11, 2025

51,890 people reported to have side effects when taking Hydroxyzine.
Among them, 3,573 people (6.89%) have Itchiness.

Among these 3,573 people:

* Approximation only. Some reports may have incomplete information.

Do you take Hydroxyzine and have Itchiness?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydroxyzine:

Hydroxyzine (54,060 reports)

Itchiness treatments and more:

Itchiness (398,803 reports)

How severe was Itchiness and when was it recovered:

Itchiness in Hydroxyzine

Expand to all the drugs that have ingredients of hydroxyzine hydrochloride:

Itchiness and drugs with ingredients of hydroxyzine hydrochloride (5,116 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Hydroxyzine side effects:

Hydroxyzine side effect: Pain (3,422 reports)
Hydroxyzine side effect: Nausea (feeling of having an urge to vomit) (3,354 reports)

Browse all side effects of Hydroxyzine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Itchiness:

Browse all the drugs that are associated with Itchiness:

Itchiness (3,379 drugs)

Common conditions associated with Itchiness:

Arthritis - rheumatoid: 20,749 reports
Plaque psoriasis: 19,506 reports
Dermatitis atopic: 18,622 reports
Ms hug: 13,880 reports
Hypertension: 13,304 reports
Blood pressure increased: 13,217 reports
Hbp: 13,212 reports
High cholesterol: 10,654 reports
Pain: 8,403 reports
Pain relief: 8,336 reports

Browse all the conditions that are associated with Itchiness:

Itchiness (4,515 conditions)

Drugs similar to Hydroxyzine and Itchiness :

Related publications that referenced our studies

Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride (the active ingredients of Hydroxyzine) and Hydroxyzine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.