Hygroton and Weight increased - a phase IV clinical study of FDA data

Summary:

Weight increased is reported as a side effect among people who take Hygroton (chlorthalidone), especially for people who are female, 60+ old, have been taking the drug for 10+ years also take Aldomet, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Weight increased when taking Hygroton. It is created by eHealthMe based on reports of 1,431 people who have side effects when taking Hygroton from the FDA, and is updated regularly.

What is Hygroton?

Hygroton has active ingredients of chlorthalidone. It is often used in high blood pressure. eHealthMe is studying from 1,463 Hygroton users. Check the latest studies of Hygroton.

What is Weight increased?

Weight increased is found to be associated with 2,885 drugs and 3,951 conditions by eHealthMe. Check the latest studies of Weight increased.

On Jul, 06, 2026

1,431 people reported to have side effects when taking Hygroton.
Among them, 34 people (2.38%) have Weight increased.

Among these 34 people:

How long have people been on Hygroton when they have Weight increased? *

What is the gender of people who have Weight increased when taking Hygroton? *

female: 87.1 %
male: 12.9 %

What is the age of people who have Weight increased when taking Hygroton? *

What are other drugs people take besides Hygroton? *

What are other side effects people have besides Weight increased? *

Joint Pain: 10 people, 29.41%
General Physical Health Deterioration (weak health status): 9 people, 26.47%
Fall: 9 people, 26.47%
Dyspnea (difficult or laboured breathing): 9 people, 26.47%
Spinal Pain (pain in spine): 9 people, 26.47%
Pulseless Electrical Activity: 4 people, 11.76%
Fever: 4 people, 11.76%
Exercise Tolerance Decreased: 4 people, 11.76%
Cyanosis Central (circulatory or ventilatory problem that leads to poor blood oxygenation in body): 4 people, 11.76%
Coughing Up Blood: 4 people, 11.76%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 11.76%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 8.82%
Joint Dislocation (a joint position is changed from normal position): 2 people, 5.88%
Essential Hypertension (primary hypertension): 2 people, 5.88%
Pain: 2 people, 5.88%
Joint Pain: 2 people, 5.88%
Weight Loss: 1 person, 2.94%
Diabetes: 1 person, 2.94%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 2.94%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 1 person, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Hygroton and have Weight increased?

- Check whether Weight increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hygroton:

Hygroton (1,463 reports)

Weight increased treatments and more:

Weight increased (279,369 reports)

Browse all side effects of Hygroton:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Weight increased:

Weight increased (2,885 drugs)

Browse all the conditions that are associated with Weight increased:

Weight increased (3,951 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on chlorthalidone (the active ingredients of Hygroton) and Hygroton (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.