Hyrimoz and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Hyrimoz (adalimumab-adaz), especially for people who are female, 40-49 old, also take Methotrexate, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Sciatica when taking Hyrimoz. It is created by eHealthMe based on reports of 4,629 people who have side effects when taking Hyrimoz from the FDA, and is updated regularly.

What is Hyrimoz?

Hyrimoz has active ingredients of adalimumab-adaz. eHealthMe is studying from 4,635 Hyrimoz users. Check the latest studies of Hyrimoz.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,146 drugs and 1,423 conditions by eHealthMe. Check the latest studies of Sciatica.



On Jan, 29, 2026

4,629 people reported to have side effects when taking Hyrimoz.
Among them, 8 people (0.17%) have Sciatica.

Could Hyrimoz cause Sciatica?

Among these 8 people:

What is the gender of people who have Sciatica when taking Hyrimoz? *

  • female: 62.5 %
  • male: 37.5 %

What is the age of people who have Sciatica when taking Hyrimoz? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 100 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

What are other drugs people take besides Hyrimoz? *

  1. Methotrexate: 6 people, 75.00%
  2. Xeljanz: 1 person, 12.50%
  3. Cimzia: 1 person, 12.50%
  4. Enbrel: 1 person, 12.50%
  5. Diclofenac Sodium: 1 person, 12.50%
  6. Desoximetasone: 1 person, 12.50%
  7. Cosentyx: 1 person, 12.50%
  8. Cortisone Acetate: 1 person, 12.50%
  9. Cetirizine Hydrochloride: 1 person, 12.50%
  10. Folic Acid: 1 person, 12.50%

What are other side effects people have besides Sciatica? *

  1. Pain: 3 people, 37.50%
  2. Initial Insomnia (feeling of inadequate or poor-quality sleep): 3 people, 37.50%
  3. Pneumonia: 3 people, 37.50%
  4. Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 37.50%
  5. Middle Insomnia (difficulty returning to sleep after awakening either in the middle of the night): 3 people, 37.50%
  6. Diarrhea: 2 people, 25.00%
  7. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 25.00%
  8. Oedema Peripheral (superficial swelling): 2 people, 25.00%
  9. Helicobacter Infection (helicobacter pylori (h. pylori) infects stomach): 1 person, 12.50%
  10. Headache (pain in head): 1 person, 12.50%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 87.50%
  2. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 12.50%
  3. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Hyrimoz and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hyrimoz:

Sciatica treatments and more:

How severe was Sciatica and when was it recovered:

Expand to all the drugs that have ingredients of adalimumab-adaz:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hyrimoz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Browse all the conditions that are associated with Sciatica:


How the study uses the data?

The study uses data from the FDA. It is based on adalimumab-adaz (the active ingredients of Hyrimoz) and Hyrimoz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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