Hyzaar and Type 1 diabetes - a phase IV clinical study of FDA data

Summary:

Type 1 diabetes is reported as a side effect among people who take Hyzaar (hydrochlorothiazide; losartan potassium), especially for people who are female, 60+ old, also take Xanax, and have Sleep disorder.

The phase IV clinical study analyzes which people have Type 1 diabetes when taking Hyzaar. It is created by eHealthMe based on reports of 15,960 people who have side effects when taking Hyzaar from the FDA, and is updated regularly.

What is Hyzaar?

Hyzaar has active ingredients of hydrochlorothiazide; losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 16,614 Hyzaar users. Check the latest studies of Hyzaar.

What is Type 1 diabetes?

Type 1 diabetes is found to be associated with 668 drugs and 1,644 conditions by eHealthMe. Check the latest studies of Type 1 diabetes.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

15,960 people reported to have side effects when taking Hyzaar.
Among them, 17 people (0.11%) have Type 1 diabetes.

Among these 17 people:

What is the gender of people who have Type 1 diabetes when taking Hyzaar? *

female: 70.59 %
male: 29.41 %

What is the age of people who have Type 1 diabetes when taking Hyzaar? *

What are other drugs people take besides Hyzaar? *

What are other side effects people have besides Type 1 diabetes? *

Type 2 Diabetes: 7 people, 41.18%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 5 people, 29.41%
Cardiac Failure Congestive: 5 people, 29.41%
Ischaemic Cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease): 5 people, 29.41%
Upper Limb Fracture: 5 people, 29.41%
Rib Fracture: 5 people, 29.41%
Chronic Renal Failure (kidney failure): 5 people, 29.41%
Osteoporosis (bones weak and more likely to break): 5 people, 29.41%
Arteriosclerosis Coronary Artery (thickening and hardening of arteries- coronary artery): 4 people, 23.53%
Lower Limb Fracture: 4 people, 23.53%

What are the existing conditions these people have? *

Sleep Disorder: 8 people, 47.06%
Pain: 6 people, 35.29%
Memory Loss: 5 people, 29.41%
Menopause (end of monthly cycles in women): 5 people, 29.41%
Apolipoprotein Abnormal: 5 people, 29.41%
Cardiac Disorder: 5 people, 29.41%
Gout (uric acid crystals building up in the body): 5 people, 29.41%
Stress And Anxiety: 4 people, 23.53%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 23.53%
Depression: 3 people, 17.65%

* Approximation only. Some reports may have incomplete information.

Do you take Hyzaar and have Type 1 diabetes?

- Check whether Type 1 diabetes is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hyzaar:

Hyzaar (16,614 reports)

Type 1 diabetes treatments and more:

Type 1 diabetes (46,846 reports)

How severe was Type 1 diabetes and when was it recovered:

Type 1 diabetes in Hyzaar

Expand to all the drugs that have ingredients of hydrochlorothiazide; losartan potassium:

Type 1 diabetes and drugs with ingredients of hydrochlorothiazide; losartan potassium (17 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hyzaar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Type 1 diabetes:

Type 1 diabetes (668 drugs)

Browse all the conditions that are associated with Type 1 diabetes:

Type 1 diabetes (1,644 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; losartan potassium (the active ingredients of Hyzaar) and Hyzaar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.