Ibrance and Fractured sacrum - a phase IV clinical study of FDA data

Summary:

Fractured sacrum is reported as a side effect among people who take Ibrance (palbociclib), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Femara, and have Breast cancer metastatic.

The phase IV clinical study analyzes which people have Fractured sacrum when taking Ibrance. It is created by eHealthMe based on reports of 104,340 people who have side effects when taking Ibrance from the FDA, and is updated regularly.

What is Ibrance?

Ibrance has active ingredients of palbociclib. eHealthMe is studying from 104,434 Ibrance users. Check the latest studies of Ibrance.

What is Fractured sacrum?

Fractured sacrum is found to be associated with 347 drugs and 384 conditions by eHealthMe. Check the latest studies of Fractured sacrum.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

104,340 people reported to have side effects when taking Ibrance.
Among them, 23 people (0.02%) have Fractured sacrum.

Among these 23 people:

How long have people been on Ibrance when they have Fractured sacrum? *

What is the gender of people who have Fractured sacrum when taking Ibrance? *

female: 100 %
male: 0.0 %

What is the age of people who have Fractured sacrum when taking Ibrance? *

What are other drugs people take besides Ibrance? *

Afinitor: 10 people, 43.48%
Femara: 10 people, 43.48%
Aromasin: 5 people, 21.74%
Stiolto Respimat: 4 people, 17.39%
Proair Hfa: 4 people, 17.39%
Duragesic: 3 people, 13.04%
Oxycodone And Acetaminophen: 3 people, 13.04%
Oxycodone: 3 people, 13.04%
Vinorelbine: 3 people, 13.04%
Lasix: 3 people, 13.04%

What are other side effects people have besides Fractured sacrum? *

Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 17 people, 73.91%
Weight Decreased: 16 people, 69.57%
Spinal Pain (pain in spine): 14 people, 60.87%
Fever: 10 people, 43.48%
Bundle Branch Block Left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle): 10 people, 43.48%
Abdominal Pain Upper: 10 people, 43.48%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 10 people, 43.48%
Acne (skin problems that cause pimples): 10 people, 43.48%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 10 people, 43.48%
Spinal Compression Fracture (fracture due to spinal compression on bone): 10 people, 43.48%

What are the existing conditions these people have? *

Breast Cancer Metastatic: 11 people, 47.83%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 17.39%
Breast Cancer: 4 people, 17.39%
Oedema Peripheral (superficial swelling): 3 people, 13.04%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.04%
Gastritis (inflammation of stomach): 3 people, 13.04%
Spinal Pain (pain in spine): 2 people, 8.70%
Joint Pain: 2 people, 8.70%
Pain: 1 person, 4.35%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Ibrance and have Fractured sacrum?

- Check whether Fractured sacrum is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibrance:

Ibrance (104,434 reports)

Browse all side effects of Ibrance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fractured sacrum:

Fractured sacrum (347 drugs)

Browse all the conditions that are associated with Fractured sacrum:

Fractured sacrum (384 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on palbociclib (the active ingredients of Ibrance) and Ibrance (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.