Ibrance and Spastic colon - a phase IV clinical study of FDA data

Summary:

Spastic colon is reported as a side effect among people who take Ibrance (palbociclib), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Letrozole, and have Breast cancer metastatic.

The phase IV clinical study analyzes which people have Spastic colon when taking Ibrance. It is created by eHealthMe based on reports of 104,340 people who have side effects when taking Ibrance from the FDA, and is updated regularly.

What is Ibrance?

Ibrance has active ingredients of palbociclib. eHealthMe is studying from 104,433 Ibrance users. Check the latest studies of Ibrance.

What is Spastic colon?

Spastic colon (repeated abdominal pain and diarrhoea) is found to be associated with 2,385 drugs and 2,156 conditions by eHealthMe. Check the latest studies of Spastic colon.

On Nov, 03, 2025

104,340 people reported to have side effects when taking Ibrance.
Among them, 68 people (0.07%) have Spastic colon.

Among these 68 people:

How long have people been on Ibrance when they have Spastic colon? *

What is the gender of people who have Spastic colon when taking Ibrance? *

female: 100 %
male: 0.0 %

What is the age of people who have Spastic colon when taking Ibrance? *

What are other drugs people take besides Ibrance? *

What are other side effects people have besides Spastic colon? *

Diarrhea: 32 people, 47.06%
Fatigue (feeling of tiredness): 18 people, 26.47%
White Blood Cell Count Decreased: 17 people, 25.00%
Neoplasm Progression (growth of tumour): 15 people, 22.06%
Nausea (feeling of having an urge to vomit): 14 people, 20.59%
Abdominal Discomfort: 14 people, 20.59%
Hair Loss: 12 people, 17.65%
Joint Pain: 9 people, 13.24%
Weakness: 9 people, 13.24%
Constipation: 9 people, 13.24%

What are the existing conditions these people have? *

Breast Cancer Female: 13 people, 19.12%
Breast Cancer Metastatic: 13 people, 19.12%
Breast Cancer Stage Iv: 8 people, 11.76%
Breast Cancer: 4 people, 5.88%
Ovarian Cancer (cancer of ovary): 3 people, 4.41%
High Blood Cholesterol: 2 people, 2.94%
Diabetes: 2 people, 2.94%
Thyroid Diseases: 2 people, 2.94%
Panic Disorder: 2 people, 2.94%
Sleep Disorder: 2 people, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Ibrance and have Spastic colon?

- Check whether Spastic colon is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibrance:

Ibrance (104,433 reports)

Spastic colon treatments and more:

Spastic colon (49,223 reports)

Browse all side effects of Ibrance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spastic colon:

Spastic colon (2,385 drugs)

Browse all the conditions that are associated with Spastic colon:

Spastic colon (2,156 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on palbociclib (the active ingredients of Ibrance) and Ibrance (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.