Ibrance and Underactive thyroid - a phase IV clinical study of FDA data
Summary:
Underactive thyroid is reported as a side effect among people who take Ibrance (palbociclib), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Faslodex, and have Breast cancer female.
The phase IV clinical study analyzes which people have Underactive thyroid when taking Ibrance. It is created by eHealthMe based on reports of 104,340 people who have side effects when taking Ibrance from the FDA, and is updated regularly.
What is Ibrance?
Ibrance has active ingredients of palbociclib. eHealthMe is studying from 104,433 Ibrance users. Check the latest studies of Ibrance.
What is Underactive thyroid?
Underactive thyroid is found to be associated with 2,777 drugs and 2,612 conditions by eHealthMe. Check the latest studies of Underactive thyroid.
104,340 people reported to have side effects when taking Ibrance.
Among them, 85 people (0.08%) have Underactive thyroid.

Among these 85 people:
How long have people been on Ibrance when they have Underactive thyroid? *
- < 1 month: 45.45 %
- 1 - 6 months: 27.27 %
- 6 - 12 months: 9.09 %
- 1 - 2 years: 18.18 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Underactive thyroid when taking Ibrance? *
- female: 97.56 %
- male: 2.44 %
What is the age of people who have Underactive thyroid when taking Ibrance? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 1.28 %
- 50-59: 12.82 %
- 60+: 85.9 %
What are other drugs people take besides Ibrance? *
- Faslodex: 15 people, 17.65%
- Arimidex: 10 people, 11.76%
- Calcium: 9 people, 10.59%
- Vitamin D3: 8 people, 9.41%
- Letrozole: 8 people, 9.41%
- Synthroid: 8 people, 9.41%
- Zometa: 6 people, 7.06%
- Femara: 6 people, 7.06%
- Fish Oil: 5 people, 5.88%
- Xgeva: 5 people, 5.88%
What are other side effects people have besides Underactive thyroid? *
- Fatigue (feeling of tiredness): 23 people, 27.06%
- Neoplasm Progression (growth of tumour): 20 people, 23.53%
- Anaemia (lack of blood): 15 people, 17.65%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 16.47%
- Pain: 13 people, 15.29%
- Dizziness: 13 people, 15.29%
- High Blood Pressure: 13 people, 15.29%
- Diabetes: 12 people, 14.12%
- Hair Loss: 12 people, 14.12%
- White Blood Cell Count Decreased: 11 people, 12.94%
What are the existing conditions these people have? *
- Breast Cancer Female: 29 people, 34.12%
- Breast Cancer Metastatic: 21 people, 24.71%
- Breast Cancer: 10 people, 11.76%
- High Blood Cholesterol: 4 people, 4.71%
- Lung Neoplasm Malignant (cancer tumour of lung): 4 people, 4.71%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 4.71%
- Irritable Bowel Syndrome: 4 people, 4.71%
- Heart Rate Irregular: 3 people, 3.53%
- High Blood Pressure: 3 people, 3.53%
- Diabetes: 3 people, 3.53%
* Approximation only. Some reports may have incomplete information.
Do you take Ibrance and have Underactive thyroid?
- Check whether Underactive thyroid is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Ibrance:
- Ibrance (104,433 reports)
Underactive thyroid treatments and more:
- Underactive thyroid (168,014 reports)
How severe was Underactive thyroid and when was it recovered:
Expand to all the drugs that have ingredients of palbociclib:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ibrance:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Underactive thyroid:
- Underactive thyroid (2,777 drugs)
Browse all the conditions that are associated with Underactive thyroid:
- Underactive thyroid (2,612 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on palbociclib (the active ingredients of Ibrance) and Ibrance (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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