Imitrex and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Imitrex (sumatriptan succinate), especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years also take Neurontin, and have Osteopenia.

The phase IV clinical study analyzes which people have Sciatica when taking Imitrex. It is created by eHealthMe based on reports of 15,815 people who have side effects when taking Imitrex from the FDA, and is updated regularly.

What is Imitrex?

Imitrex has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 17,149 Imitrex users. Check the latest studies of Imitrex.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,151 drugs and 1,415 conditions by eHealthMe. Check the latest studies of Sciatica.

On Sep, 21, 2025

15,815 people reported to have side effects when taking Imitrex.
Among them, 20 people (0.13%) have Sciatica.

Among these 20 people:

How long have people been on Imitrex when they have Sciatica? *

What is the gender of people who have Sciatica when taking Imitrex? *

female: 95 %
male: 5 %

What is the age of people who have Sciatica when taking Imitrex? *

What are other drugs people take besides Imitrex? *

What are other side effects people have besides Sciatica? *

Fall: 11 people, 55.00%
Joint Pain: 10 people, 50.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 35.00%
Pain In Extremity: 7 people, 35.00%
Femur Fracture: 7 people, 35.00%
High Blood Pressure: 7 people, 35.00%
Sleep Apnea Syndrome: 7 people, 35.00%
Hoarseness Or Changing Voice: 7 people, 35.00%
Vision Blurred: 7 people, 35.00%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 6 people, 30.00%

What are the existing conditions these people have? *

Osteopenia (a condition where bone mineral density is lower than normal): 6 people, 30.00%
Alcoholism (problems with alcohol): 3 people, 15.00%
Breakthrough Pain: 3 people, 15.00%
Pain: 3 people, 15.00%
Neck Pain: 3 people, 15.00%
Impaired Gastric Emptying: 1 person, 5.00%
Allergic Rhinitis: 1 person, 5.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.00%
Dyslipidaemia (abnormal amount of lipids): 1 person, 5.00%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Imitrex and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imitrex:

Imitrex (17,149 reports)

Sciatica treatments and more:

Sciatica (28,503 reports)

Browse all side effects of Imitrex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Sciatica (1,151 drugs)

Browse all the conditions that are associated with Sciatica:

Sciatica (1,415 conditions)

Drugs similar to Imitrex and Sciatica :

How the study uses the data?

The study uses data from the FDA. It is based on sumatriptan succinate (the active ingredients of Imitrex) and Imitrex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.