Implanon and Vaginal bleeding - a phase IV clinical study of FDA data

Summary:

Vaginal bleeding is reported as a side effect among people who take Implanon (etonogestrel), especially for people who are 20-29 old, have been taking the drug for 2 - 5 years also take Nexplanon, and have Epilepsy.

The phase IV clinical study analyzes which people have Vaginal bleeding when taking Implanon. It is created by eHealthMe based on reports of 11,921 people who have side effects when taking Implanon from the FDA, and is updated regularly.

What is Implanon?

Implanon has active ingredients of etonogestrel. It is often used in birth control. eHealthMe is studying from 12,479 Implanon users. Check the latest studies of Implanon.

What is Vaginal bleeding?

Vaginal bleeding is found to be associated with 1,143 drugs and 1,512 conditions by eHealthMe. Check the latest studies of Vaginal bleeding.

On Apr, 20, 2026

11,921 people reported to have side effects when taking Implanon.
Among them, 334 people (2.8%) have Vaginal bleeding.

Among these 334 people:

* Approximation only. Some reports may have incomplete information.

Do you take Implanon and have Vaginal bleeding?

- Check whether Vaginal bleeding is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Implanon:

Implanon (12,479 reports)

Vaginal bleeding treatments and more:

Vaginal bleeding (49,485 reports)

How severe was Vaginal bleeding and when was it recovered:

Vaginal bleeding in Implanon

Expand to all the drugs that have ingredients of etonogestrel:

Vaginal bleeding and drugs with ingredients of etonogestrel (2,124 reports)

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Implanon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Vaginal bleeding:

Vaginal bleeding (1,143 drugs)

Browse all the conditions that are associated with Vaginal bleeding:

Vaginal bleeding (1,512 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on etonogestrel (the active ingredients of Implanon) and Implanon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.