Imuran and Irritability - a phase IV clinical study of FDA data

Summary:

Irritability is reported as a side effect among people who take Imuran (azathioprine), especially for people who are female, 40-49 old, have been taking the drug for 6 - 12 months also take Prednisone, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Irritability when taking Imuran. It is created by eHealthMe based on reports of 34,190 people who have side effects when taking Imuran from the FDA, and is updated regularly.

What is Imuran?

Imuran has active ingredients of azathioprine. It is often used in crohn's disease. eHealthMe is studying from 34,915 Imuran users. Check the latest studies of Imuran.

What is Irritability?

Irritability is found to be associated with 1,700 drugs and 2,458 conditions by eHealthMe. Check the latest studies of Irritability.

On Jul, 13, 2026

34,190 people reported to have side effects when taking Imuran.
Among them, 64 people (0.19%) have Irritability.

Among these 64 people:

How long have people been on Imuran when they have Irritability? *

What is the gender of people who have Irritability when taking Imuran? *

female: 82.76 %
male: 17.24 %

What is the age of people who have Irritability when taking Imuran? *

What are other drugs people take besides Imuran? *

What are other side effects people have besides Irritability? *

Fatigue (feeling of tiredness): 33 people, 51.56%
Stress And Anxiety: 16 people, 25.00%
Depression: 14 people, 21.88%
Headache (pain in head): 14 people, 21.88%
Joint Pain: 13 people, 20.31%
Weight Increased: 12 people, 18.75%
Mood Swings (an extreme or rapid change in mood): 12 people, 18.75%
Nausea (feeling of having an urge to vomit): 12 people, 18.75%
Dry Skin: 11 people, 17.19%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 10 people, 15.62%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 9.38%
Acne (skin problems that cause pimples): 5 people, 7.81%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 6.25%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 4.69%
Pain: 3 people, 4.69%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 4.69%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 3.12%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 2 people, 3.12%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 2 people, 3.12%
Blood Pressure Abnormal: 2 people, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Imuran and have Irritability?

- Check whether Irritability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imuran:

Imuran (34,915 reports)

Irritability treatments and more:

Irritability (71,614 reports)

Browse all side effects of Imuran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Irritability:

Irritability (1,700 drugs)

Browse all the conditions that are associated with Irritability:

Irritability (2,458 conditions)

Related publications that referenced our studies

Almarshad HA, "Effect of ginger rhizome extract on lymphocytopenic guinea pig with azathioprine", African Journal of Pharmacy and Pharmacology, 2014 Nov .
Almarshad HA, "Effect of ginger rhizome extract on lymphocytopenic guinea pig with azathioprine", African Journal of Pharmacy and Pharmacology, 2014 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on azathioprine (the active ingredients of Imuran) and Imuran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.