Imuran and Muscle spasticity - a phase IV clinical study of FDA data

Summary:

Muscle spasticity is reported as a side effect among people who take Imuran (azathioprine), especially for people who are female, 20-29 old, also take Medrol, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Muscle spasticity when taking Imuran. It is created by eHealthMe based on reports of 34,190 people who have side effects when taking Imuran from the FDA, and is updated regularly.

What is Imuran?

Imuran has active ingredients of azathioprine. It is often used in crohn's disease. eHealthMe is studying from 34,915 Imuran users. Check the latest studies of Imuran.

What is Muscle spasticity?

Muscle spasticity (tight or stiff muscles and an inability to control those muscles) is found to be associated with 720 drugs and 667 conditions by eHealthMe. Check the latest studies of Muscle spasticity.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

34,190 people reported to have side effects when taking Imuran.
Among them, 14 people (0.04%) have Muscle spasticity.

Among these 14 people:

What is the gender of people who have Muscle spasticity when taking Imuran? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Muscle spasticity when taking Imuran? *

What are other drugs people take besides Imuran? *

What are other side effects people have besides Muscle spasticity? *

Dizziness: 6 people, 42.86%
Hypoaesthesia (reduced sense of touch or sensation): 6 people, 42.86%
Nausea And Vomiting: 6 people, 42.86%
Fever: 5 people, 35.71%
Headache (pain in head): 5 people, 35.71%
Paresis (a condition of muscular weakness): 5 people, 35.71%
Hypotension (abnormally low blood pressure): 4 people, 28.57%
Pain: 4 people, 28.57%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 4 people, 28.57%
Muscle Aches (muscle pain): 4 people, 28.57%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 35.71%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 21.43%
Ventricular Extrasystoles (premature cardiac contraction): 1 person, 7.14%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%
Pain: 1 person, 7.14%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 7.14%
Gait Disturbance: 1 person, 7.14%
Cystitis Interstitial (unknown cause characterized by bladder pain): 1 person, 7.14%
Arrhythmias (irregular heartbeat): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Imuran and have Muscle spasticity?

- Check whether Muscle spasticity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Imuran:

Imuran (34,915 reports)

Browse all side effects of Imuran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle spasticity:

Muscle spasticity (720 drugs)

Browse all the conditions that are associated with Muscle spasticity:

Muscle spasticity (667 conditions)

Related publications that referenced our studies

Almarshad HA, "Effect of ginger rhizome extract on lymphocytopenic guinea pig with azathioprine", African Journal of Pharmacy and Pharmacology, 2014 Nov .
Almarshad HA, "Effect of ginger rhizome extract on lymphocytopenic guinea pig with azathioprine", African Journal of Pharmacy and Pharmacology, 2014 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on azathioprine (the active ingredients of Imuran) and Imuran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.