Ursodiol and Pericardial effusion - a phase IV clinical study of FDA data

Summary:

Pericardial effusion is reported as a side effect among people who take Ursodiol (ursodiol), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tacrolimus, and have Acute myeloid leukaemia.

The phase IV clinical study analyzes which people have Pericardial effusion when taking Ursodiol. It is created by eHealthMe based on reports of 18,820 people who have side effects when taking Ursodiol from the FDA, and is updated regularly.

What is Ursodiol?

Ursodiol has active ingredients of ursodiol. It is often used in primary biliary cirrhosis. eHealthMe is studying from 19,061 Ursodiol users. Check the latest studies of Ursodiol.

What is Pericardial effusion?

Pericardial effusion (fluid around the heart) is found to be associated with 1,402 drugs and 1,462 conditions by eHealthMe. Check the latest studies of Pericardial effusion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

18,820 people reported to have side effects when taking Ursodiol.
Among them, 100 people (0.53%) have Pericardial effusion.

Could Ursodiol cause Pericardial effusion?

Among these 100 people:

How long have people been on Ursodiol when they have Pericardial effusion? *

What is the gender of people who have Pericardial effusion when taking Ursodiol? *

female: 57.29 %
male: 42.71 %

What is the age of people who have Pericardial effusion when taking Ursodiol? *

What are other drugs people take besides Ursodiol? *

Cyclophosphamide: 43 people, 43.00%
Tacrolimus: 43 people, 43.00%
Busulfan: 40 people, 40.00%
Thiotepa: 39 people, 39.00%
Mycophenolate Mofetil: 37 people, 37.00%
Melphalan: 21 people, 21.00%
Ativan: 18 people, 18.00%
Zofran: 17 people, 17.00%
Morphine: 14 people, 14.00%
Ondansetron: 14 people, 14.00%

What are other side effects people have besides Pericardial effusion? *

Ascites (accumulation of fluid in the abdominal cavity): 51 people, 51.00%
Pleural Effusion (water on the lungs): 43 people, 43.00%
Hepatic Failure (liver failure): 27 people, 27.00%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 23 people, 23.00%
Thrombocytopenia (decrease of platelets in blood): 20 people, 20.00%
Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 19 people, 19.00%
Nausea (feeling of having an urge to vomit): 18 people, 18.00%
Fever: 18 people, 18.00%
Chest Pain: 18 people, 18.00%
Cytomegalovirus Urinary Tract Infection (infection with cytomegalo virus): 16 people, 16.00%

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 37 people, 37.00%
Bone Marrow Conditioning Regimen: 18 people, 18.00%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 10 people, 10.00%
Constipation: 10 people, 10.00%
Pain: 8 people, 8.00%
Nausea (feeling of having an urge to vomit): 8 people, 8.00%
Nausea And Vomiting: 8 people, 8.00%
Stress And Anxiety: 7 people, 7.00%
Insomnia (sleeplessness): 6 people, 6.00%
Blood Uric Acid Increased: 5 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Ursodiol and have Pericardial effusion?

- Check whether Pericardial effusion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ursodiol:

Ursodiol (19,061 reports)

Browse all side effects of Ursodiol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pericardial effusion:

Pericardial effusion (1,402 drugs)

Browse all the conditions that are associated with Pericardial effusion:

Pericardial effusion (1,462 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ursodiol (the active ingredients of Ursodiol) and Ursodiol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.