Invokamet and Dehydration - a phase IV clinical study of FDA data

Summary:

Dehydration is reported as a side effect among people who take Invokamet (canagliflozin; metformin hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Invokana, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Dehydration when taking Invokamet. It is created by eHealthMe based on reports of 1,957 people who have side effects when taking Invokamet from the FDA, and is updated regularly.

What is Invokamet?

Invokamet has active ingredients of canagliflozin; metformin hydrochloride. eHealthMe is studying from 1,965 Invokamet users. Check the latest studies of Invokamet.

What is Dehydration?

Dehydration (dryness resulting from the removal of water) is found to be associated with 2,756 drugs and 3,349 conditions by eHealthMe. Check the latest studies of Dehydration.

On Jul, 11, 2026

1,957 people reported to have side effects when taking Invokamet.
Among them, 44 people (2.25%) have Dehydration.

Among these 44 people:

How long have people been on Invokamet when they have Dehydration? *

What is the gender of people who have Dehydration when taking Invokamet? *

female: 52.63 %
male: 47.37 %

What is the age of people who have Dehydration when taking Invokamet? *

What are other drugs people take besides Invokamet? *

What are other side effects people have besides Dehydration? *

Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 9 people, 20.45%
Nausea (feeling of having an urge to vomit): 6 people, 13.64%
Nausea And Vomiting: 5 people, 11.36%
Blood Glucose Increased: 5 people, 11.36%
Dizziness: 4 people, 9.09%
Fainting (loss of consciousness and postural tone): 4 people, 9.09%
Insomnia (sleeplessness): 4 people, 9.09%
Diarrhea: 4 people, 9.09%
Acute Kidney Failure: 4 people, 9.09%
Seasonal Allergy (allergic condition due to certain season): 3 people, 6.82%

What are the existing conditions these people have? *

Type 2 Diabetes: 26 people, 59.09%
Diabetes: 11 people, 25.00%
High Blood Pressure: 4 people, 9.09%
Neuropathy Peripheral (surface nerve damage): 2 people, 4.55%
Weight Decreased: 1 person, 2.27%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 2.27%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 2.27%
Insomnia (sleeplessness): 1 person, 2.27%
Hypotension (abnormally low blood pressure): 1 person, 2.27%
Hypoaesthesia (reduced sense of touch or sensation): 1 person, 2.27%

* Approximation only. Some reports may have incomplete information.

Do you take Invokamet and have Dehydration?

- Check whether Dehydration is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Invokamet:

Invokamet (1,965 reports)

Dehydration treatments and more:

Dehydration (173,274 reports)

How severe was Dehydration and when was it recovered:

Dehydration in Invokamet

Expand to all the drugs that have ingredients of canagliflozin; metformin hydrochloride:

Dehydration and drugs with ingredients of canagliflozin; metformin hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Invokamet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dehydration:

Dehydration (2,756 drugs)

Browse all the conditions that are associated with Dehydration:

Dehydration (3,349 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on canagliflozin; metformin hydrochloride (the active ingredients of Invokamet) and Invokamet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.