Acetazolamide and Vicodin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acetazolamide (acetazolamide) and Vicodin (acetaminophen; hydrocodone bitartrate). Common drug interactions include pruritus among females and faecaloma among males.

The phase IV clinical study analyzes what interactions people have when they take Acetazolamide and Vicodin. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Acetazolamide?

Acetazolamide has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 6,178 Acetazolamide users. Check the latest studies of Acetazolamide.

What is Vicodin?

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 63,357 Vicodin users. Check the latest studies of Vicodin.

On Jul, 11, 2026

67 people who take Acetazolamide and Vicodin together, and have interactions are studied.

Acetazolamide and Vicodin drug interactions.

What are the common drug interactions of Acetazolamide and Vicodin, by gender? *:

female:

Pruritus (severe itching of the skin)
Rhinorrhoea (watery mucus discharge from the nose)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Tenderness (pain or discomfort when an affected area is touched)
Abdominal discomfort
Bone disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Cluster headache (one-sided head pain with tearing)
Csf pressure increased

male:

Faecaloma (hard mass of fecal matter)
Malaise (a feeling of general discomfort or uneasiness)
Rib fracture
Tooth fracture
Abdominal discomfort
Depression
Head injury
Hypoacusis (loss of hearing)
Hypoaesthesia (reduced sense of touch or sensation)
Injury

What are the common drug interactions of Acetazolamide and Vicodin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Emotional distress
Fibromyalgia (a long-term condition which causes pain all over the body)
Injury
Migraine (headache)
Ovarian cyst (fluid filled sac of the ovary)

30-39:

Migraine (headache)
Nausea (feeling of having an urge to vomit)
Abnormal dreams
Adverse drug reaction
Anxiety
Blood prolactin decreased
Bone disorder
Cardiac failure congestive
Cataract (clouding of the lens inside the eye)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

40-49:

Headache (pain in head)
Hysterectomy
Dysfunctional uterine bleeding
Anxiety
Nausea (feeling of having an urge to vomit)
Somnolence (a state of near-sleep, a strong desire for sleep)
Nephrolithiasis (calculi in the kidneys)
Drug abuse
Fungal infection
Rash

50-59:

Abscess limb (limb infection)
Anal abscess
Chronic kidney disease
Erythema (redness of the skin)
Groin abscess (pus in groin)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Sepsis (a severe blood infection that can lead to organ failure and death)

60+:

Confusional state
Diarrhoea
Eye pruritus (eye itching)
Eyelid ptosis (falling of the upper or lower eyelid)
Abdominal pain
Abnormal dreams
Asthenia (weakness)
Constipation
Fatigue (feeling of tiredness)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)

What are the existing conditions these people have? *

High Blood Pressure: 22 people, 32.84%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 22 people, 32.84%
Depression: 22 people, 32.84%
Tremor (trembling or shaking movements in one or more parts of your body): 20 people, 29.85%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 20 people, 29.85%
Tumor: 20 people, 29.85%
Muscle Spasms (muscle contraction): 20 people, 29.85%
Asthma: 20 people, 29.85%
Memory Loss: 18 people, 26.87%
Pulmonary Embolism (blockage of the main artery of the lung): 18 people, 26.87%

* Approximation only. Some reports may have incomplete information.

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