Loperamide hydrochloride and Dyazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loperamide hydrochloride (loperamide hydrochloride) and Dyazide (hydrochlorothiazide; triamterene). Common drug interactions include fatigue among females and neuropathy peripheral among males.

The phase IV clinical study analyzes what interactions people have when they take Loperamide hydrochloride and Dyazide. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Loperamide hydrochloride?

Loperamide hydrochloride has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 10,814 Loperamide hydrochloride users. Check the latest studies of Loperamide hydrochloride.

What is Dyazide?

Dyazide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 11,506 Dyazide users. Check the latest studies of Dyazide.

On Jul, 11, 2026

12 people who take Loperamide hydrochloride and Dyazide together, and have interactions are studied.

Loperamide hydrochloride and Dyazide drug interactions.

What are the common drug interactions of Loperamide Hydrochloride and Dyazide, by gender? *:

female:

Fatigue (feeling of tiredness)
Back pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Chills (felling of cold)
Constipation
Contusion (a type of hematoma of tissue in which capillaries)
Dizziness
Drug hypersensitivity
Dry skin
Dysphagia (a condition in which swallowing is difficult or painful)

male:

Neuropathy peripheral (surface nerve damage)

What are the common drug interactions of Loperamide Hydrochloride and Dyazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Muscle spasms (muscle contraction)
Restless legs syndrome (a powerful urge to move your legs)

50-59:

Overdose

60+:

Fatigue (feeling of tiredness)
Asthenia (weakness)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Chills (felling of cold)
Constipation
Contusion (a type of hematoma of tissue in which capillaries)
Dizziness
Drug hypersensitivity
Dry skin
Dysphagia (a condition in which swallowing is difficult or painful)

What are the existing conditions these people have? *

Dizziness: 4 people, 33.33%
Depression: 3 people, 25.00%
Multiple Myeloma (cancer of the plasma cells): 2 people, 16.67%
Stress And Anxiety: 1 person, 8.33%
Pain: 1 person, 8.33%
Joint Swelling: 1 person, 8.33%
Joint Pain: 1 person, 8.33%
High Blood Cholesterol: 1 person, 8.33%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 8.33%
Flatulence (flatus expelled through the anus): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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