Isoniazid and Abnormal behavior - a phase IV clinical study of FDA data

Summary:

Abnormal behavior is reported as a side effect among people who take Isoniazid (isoniazid), especially for people who are male, 50-59 old, have been taking the drug for 1 - 6 months also take Prednisolone, and have Latent tuberculosis.

The phase IV clinical study analyzes which people have Abnormal behavior when taking Isoniazid. It is created by eHealthMe based on reports of 19,852 people who have side effects when taking Isoniazid from the FDA, and is updated regularly.

What is Isoniazid?

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. eHealthMe is studying from 20,174 Isoniazid users. Check the latest studies of Isoniazid.

What is Abnormal behavior?

Abnormal behavior is found to be associated with 1,366 drugs and 1,948 conditions by eHealthMe. Check the latest studies of Abnormal behavior.



On Jul, 13, 2026

19,852 people reported to have side effects when taking Isoniazid.
Among them, 16 people (0.08%) have Abnormal behavior.

Could Isoniazid cause Abnormal behavior?

Among these 16 people:

How long have people been on Isoniazid when they have Abnormal behavior? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Abnormal behavior when taking Isoniazid? *

  • female: 13.33 %
  • male: 86.67 %

What is the age of people who have Abnormal behavior when taking Isoniazid? *

  • 0-1: 7.14 %
  • 2-9: 0.0 %
  • 10-19: 7.14 %
  • 20-29: 0.0 %
  • 30-39: 7.14 %
  • 40-49: 21.43 %
  • 50-59: 42.86 %
  • 60+: 14.29 %

What are other drugs people take besides Isoniazid? *

  1. Nevirapine: 2 people, 12.50%
  2. Vitamin B6: 2 people, 12.50%
  3. Metformin: 2 people, 12.50%
  4. Stavudine: 2 people, 12.50%
  5. Zidovudine: 2 people, 12.50%
  6. Efavirenz: 2 people, 12.50%
  7. Pyrazinamide: 2 people, 12.50%
  8. Prednisolone: 2 people, 12.50%
  9. Zovirax: 1 person, 6.25%
  10. Didronel: 1 person, 6.25%

What are other side effects people have besides Abnormal behavior? *

  1. Agitation (state of anxiety or nervous excitement): 4 people, 25.00%
  2. Headache (pain in head): 3 people, 18.75%
  3. Anaemia (lack of blood): 3 people, 18.75%
  4. Loss Of Consciousness: 3 people, 18.75%
  5. Speech Impairment (Adult) (inability to speak (adult)): 3 people, 18.75%
  6. Mania (a state of abnormally elevated or irritable mood): 2 people, 12.50%
  7. Libido Increased (increased sexual urge to have sex): 2 people, 12.50%
  8. Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 2 people, 12.50%
  9. Irritability: 2 people, 12.50%
  10. Dehydration (dryness resulting from the removal of water): 2 people, 12.50%

What are the existing conditions these people have? *

  1. Mania (a state of abnormally elevated or irritable mood): 2 people, 12.50%
  2. Latent Tuberculosis (hidden tuberculosis): 2 people, 12.50%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.25%
  4. Liver Disorder (liver diseases): 1 person, 6.25%
  5. Infectious Pleural Effusion (infectious fluid in the lung): 1 person, 6.25%
  6. Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 6.25%
  7. Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 1 person, 6.25%
  8. Herpes Zoster: 1 person, 6.25%
  9. Disseminated Tuberculosis: 1 person, 6.25%
  10. Constipation: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Isoniazid and have Abnormal behavior?

- Check whether Abnormal behavior is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isoniazid:

Abnormal behavior treatments and more:

How severe was Abnormal behavior and when was it recovered:

Expand to all the drugs that have ingredients of isoniazid:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isoniazid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Abnormal behavior:

Browse all the conditions that are associated with Abnormal behavior:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on isoniazid (the active ingredients of Isoniazid) and Isoniazid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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