Isoniazid and Haemodynamic instability - a phase IV clinical study of FDA data

Summary:

Haemodynamic instability is reported as a side effect among people who take Isoniazid (isoniazid), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Rifampin, and have Meningitis tuberculous.

The phase IV clinical study analyzes which people have Haemodynamic instability when taking Isoniazid. It is created by eHealthMe based on reports of 19,852 people who have side effects when taking Isoniazid from the FDA, and is updated regularly.

What is Isoniazid?

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. eHealthMe is studying from 20,174 Isoniazid users. Check the latest studies of Isoniazid.

What is Haemodynamic instability?

Haemodynamic instability (disturbances in the blood movement in our body) is found to be associated with 550 drugs and 1,281 conditions by eHealthMe. Check the latest studies of Haemodynamic instability.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

19,852 people reported to have side effects when taking Isoniazid.
Among them, 16 people (0.08%) have Haemodynamic instability.

Could Isoniazid cause Haemodynamic instability?

Among these 16 people:

How long have people been on Isoniazid when they have Haemodynamic instability? *

What is the gender of people who have Haemodynamic instability when taking Isoniazid? *

female: 60 %
male: 40 %

What is the age of people who have Haemodynamic instability when taking Isoniazid? *

What are other drugs people take besides Isoniazid? *

What are other side effects people have besides Haemodynamic instability? *

Hypotension (abnormally low blood pressure): 6 people, 37.50%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 4 people, 25.00%
Consciousness - Decreased: 3 people, 18.75%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 3 people, 18.75%
Hyperkalemia (damage to or disease of the kidney): 3 people, 18.75%
Suicide Attempt: 3 people, 18.75%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 18.75%
Lactic Acidosis (low ph in body tissues): 3 people, 18.75%
Loss Of Consciousness: 3 people, 18.75%
Overdose: 2 people, 12.50%

What are the existing conditions these people have? *

Meningitis Tuberculous (a bacterial infection of the membranes covering the brain and spinal cord (meninges)): 3 people, 18.75%
Encephalitis (inflammation of the brain): 2 people, 12.50%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 6.25%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.25%
Respiratory Distress (difficulty in breathing): 1 person, 6.25%
Osteoporosis (bones weak and more likely to break): 1 person, 6.25%
Mastitis Bacterial (bacterial infection of breast): 1 person, 6.25%
Lymphadenitis (inflammation or enlargement of a lymph node): 1 person, 6.25%
Latent Tuberculosis (hidden tuberculosis): 1 person, 6.25%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Isoniazid and have Haemodynamic instability?

- Check whether Haemodynamic instability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isoniazid:

Isoniazid (20,174 reports)

Browse all side effects of Isoniazid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Haemodynamic instability:

Haemodynamic instability (550 drugs)

Browse all the conditions that are associated with Haemodynamic instability:

Haemodynamic instability (1,281 conditions)

Related publications that referenced our studies

Ganguly, R. J., Abraham, R. R., Prasad, R., & Rao, B. C, "Hyperglycaemia induced by isoniazid preventive therapy", Journal of Family Medicine and Primary Care, 2018 Jan .
Ganguly, R. J., Abraham, R. R., Prasad, R., & Rao, B. C, "Hyperglycaemia induced by isoniazid preventive therapy", Journal of Family Medicine and Primary Care, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on isoniazid (the active ingredients of Isoniazid) and Isoniazid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.