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Isoniazid and Hearing loss - a phase IV clinical study of FDA data

Summary:

Hearing loss is reported as a side effect among people who take Isoniazid (isoniazid), especially for people who are male, 20-29 old, have been taking the drug for 6 - 12 months also take Pyrazinamide, and have Disseminated tuberculosis.

The phase IV clinical study analyzes which people have Hearing loss when taking Isoniazid. It is created by eHealthMe based on reports of 19,852 people who have side effects when taking Isoniazid from the FDA, and is updated regularly.

What is Isoniazid?

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. eHealthMe is studying from 20,174 Isoniazid users. Check the latest studies of Isoniazid.

What is Hearing loss?

Hearing loss is found to be associated with 1,358 drugs and 2,378 conditions by eHealthMe. Check the latest studies of Hearing loss.

On Jul, 13, 2026

19,852 people reported to have side effects when taking Isoniazid.
Among them, 34 people (0.17%) have Hearing loss.

Could Isoniazid cause Hearing loss?

Among these 34 people:

How long have people been on Isoniazid when they have Hearing loss? *

  • < 1 month: 12.5 %
  • 1 - 6 months: 37.5 %
  • 6 - 12 months: 50.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hearing loss when taking Isoniazid? *

  • female: 17.24 %
  • male: 82.76 %

What is the age of people who have Hearing loss when taking Isoniazid? *

  • 0-1: 19.23 %
  • 2-9: 0.0 %
  • 10-19: 3.85 %
  • 20-29: 26.92 %
  • 30-39: 23.08 %
  • 40-49: 11.54 %
  • 50-59: 7.69 %
  • 60+: 7.69 %

What are other drugs people take besides Isoniazid? *

  1. Pyrazinamide: 11 people, 32.35%
  2. Rifampin: 10 people, 29.41%
  3. Linezolid: 8 people, 23.53%
  4. Kanamycin: 6 people, 17.65%
  5. Levofloxacin: 5 people, 14.71%
  6. Moxifloxacin: 3 people, 8.82%
  7. Fluconazole: 3 people, 8.82%
  8. Phenytoin: 3 people, 8.82%
  9. Amikacin Sulfate: 3 people, 8.82%
  10. Busulfan: 3 people, 8.82%

What are other side effects people have besides Hearing loss? *

  1. Neuropathy Peripheral (surface nerve damage): 7 people, 20.59%
  2. Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 5 people, 14.71%
  3. Hemianopia Heteronymous (loss of vision in either both nasal halves or both temporal halves of the visual field): 4 people, 11.76%
  4. High Blood Pressure: 4 people, 11.76%
  5. Anaemia (lack of blood): 4 people, 11.76%
  6. Blindness: 4 people, 11.76%
  7. Cushing's Syndrome (obesity, a rounded face, increased fat): 4 people, 11.76%
  8. Visual Impairment: 3 people, 8.82%
  9. Drug-Induced Liver Injury (diseases of the liver that are caused by physician-prescribed medications): 3 people, 8.82%
  10. Drug Resistance (reduction in effectiveness of a drug): 3 people, 8.82%

What are the existing conditions these people have? *

  1. Meningitis Tuberculous (a bacterial infection of the membranes covering the brain and spinal cord (meninges)): 4 people, 11.76%
  2. Disseminated Tuberculosis: 4 people, 11.76%
  3. Bone Tuberculosis: 3 people, 8.82%
  4. Tuberculosis Of Genitourinary System (a bacterial infection of genitourinary tract by mycobacterium tuberculosis): 2 people, 5.88%
  5. Tuberculosis Bladder (a bacterial infection of bladder by mycobacterium tuberculosis): 2 people, 5.88%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 5.88%
  7. Bone Marrow Conditioning Regimen: 2 people, 5.88%
  8. Pneumonia: 1 person, 2.94%
  9. Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 2.94%
  10. Neuropathy Peripheral (surface nerve damage): 1 person, 2.94%

* Approximation only. Some reports may have incomplete information.

Do you take Isoniazid and have Hearing loss?

- Check whether Hearing loss is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isoniazid:

Hearing loss treatments and more:

How severe was Hearing loss and when was it recovered:

Expand to all the drugs that have ingredients of isoniazid:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isoniazid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hearing loss:

Browse all the conditions that are associated with Hearing loss:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on isoniazid (the active ingredients of Isoniazid) and Isoniazid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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