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Isoniazid and Hepatitis cholestatic - a phase IV clinical study of FDA data

Summary:

Hepatitis cholestatic is reported as a side effect among people who take Isoniazid (isoniazid), especially for people who are male, 40-49 old, have been taking the drug for 1 - 6 months also take Rifampin, and have Hiv infection.

The phase IV clinical study analyzes which people have Hepatitis cholestatic when taking Isoniazid. It is created by eHealthMe based on reports of 19,852 people who have side effects when taking Isoniazid from the FDA, and is updated regularly.

What is Isoniazid?

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. eHealthMe is studying from 20,174 Isoniazid users. Check the latest studies of Isoniazid.

What is Hepatitis cholestatic?

Hepatitis cholestatic (flow of bile from the liver is slowed or blocked) is found to be associated with 541 drugs and 824 conditions by eHealthMe. Check the latest studies of Hepatitis cholestatic.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

19,852 people reported to have side effects when taking Isoniazid.
Among them, 83 people (0.42%) have Hepatitis cholestatic.

Could Isoniazid cause Hepatitis cholestatic?

Among these 83 people:

How long have people been on Isoniazid when they have Hepatitis cholestatic? *

  • < 1 month: 5.88 %
  • 1 - 6 months: 82.35 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 11.76 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hepatitis cholestatic when taking Isoniazid? *

  • female: 23.61 %
  • male: 76.39 %

What is the age of people who have Hepatitis cholestatic when taking Isoniazid? *

  • 0-1: 0.0 %
  • 2-9: 6.15 %
  • 10-19: 0.0 %
  • 20-29: 12.31 %
  • 30-39: 24.62 %
  • 40-49: 46.15 %
  • 50-59: 3.08 %
  • 60+: 7.69 %

What are other drugs people take besides Isoniazid? *

  1. Rifampin: 43 people, 51.81%
  2. Pyrazinamide: 40 people, 48.19%
  3. Meropenem: 38 people, 45.78%
  4. Levofloxacin: 33 people, 39.76%
  5. Efavirenz: 32 people, 38.55%
  6. Ritonavir: 32 people, 38.55%
  7. Clarithromycin: 31 people, 37.35%
  8. Ganciclovir: 31 people, 37.35%
  9. Fluconazole: 30 people, 36.14%
  10. Truvada: 30 people, 36.14%

What are other side effects people have besides Hepatitis cholestatic? *

  1. Nausea (feeling of having an urge to vomit): 36 people, 43.37%
  2. Pancreatitis (inflammation of pancreas): 30 people, 36.14%
  3. Diarrhea: 29 people, 34.94%
  4. Muscle Aches (muscle pain): 28 people, 33.73%
  5. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 28 people, 33.73%
  6. Drug Resistance (reduction in effectiveness of a drug): 27 people, 32.53%
  7. Lymphopenia (an abnormally low level of lymphocytes in the blood): 25 people, 30.12%
  8. Pathogen Resistance: 24 people, 28.92%
  9. Clostridium Difficile Colitis (inflammation of colon by clostridium difficile bacteria infection): 24 people, 28.92%
  10. Urinary Tract Infection: 23 people, 27.71%

What are the existing conditions these people have? *

  1. Hiv Infection: 29 people, 34.94%
  2. Cytomegalovirus Chorioretinitis (infection of choroid and retina of the eye from virus): 25 people, 30.12%
  3. Urinary Tract Infection: 24 people, 28.92%
  4. H1n1 Influenza (flu (influenza), which is caused by virus influenza a (h1n1)): 23 people, 27.71%
  5. Enterobacter Infection (infection caused by bacteria of the family enterobacteriaceae): 21 people, 25.30%
  6. Toxoplasmosis (a parasitic disease caused by the protozoan toxoplasma gondii): 21 people, 25.30%
  7. Urinary Tract Inflammation: 12 people, 14.46%
  8. Latent Tuberculosis (hidden tuberculosis): 11 people, 13.25%
  9. Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 11 people, 13.25%
  10. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 7 people, 8.43%

* Approximation only. Some reports may have incomplete information.

Do you take Isoniazid and have Hepatitis cholestatic?

- Check whether Hepatitis cholestatic is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isoniazid:

Hepatitis cholestatic treatments and more:

How severe was Hepatitis cholestatic and when was it recovered:

Expand to all the drugs that have ingredients of isoniazid:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isoniazid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatitis cholestatic:

Browse all the conditions that are associated with Hepatitis cholestatic:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on isoniazid (the active ingredients of Isoniazid) and Isoniazid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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