Isoniazid and Splenic abscess - a phase IV clinical study of FDA data

Summary:

Splenic abscess is reported as a side effect among people who take Isoniazid (isoniazid), especially for people who are male, 20-29 old, have been taking the drug for 6 - 12 months also take Pyrazinamide, and have Psoriasis.

The phase IV clinical study analyzes which people have Splenic abscess when taking Isoniazid. It is created by eHealthMe based on reports of 19,852 people who have side effects when taking Isoniazid from the FDA, and is updated regularly.

What is Isoniazid?

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. eHealthMe is studying from 20,174 Isoniazid users. Check the latest studies of Isoniazid.

What is Splenic abscess?

Splenic abscess (pus in spleen or near by) is found to be associated with 66 drugs and 169 conditions by eHealthMe. Check the latest studies of Splenic abscess.

On Jul, 15, 2026

19,852 people reported to have side effects when taking Isoniazid.
Among them, 16 people (0.08%) have Splenic abscess.

Among these 16 people:

How long have people been on Isoniazid when they have Splenic abscess? *

What is the gender of people who have Splenic abscess when taking Isoniazid? *

female: 20 %
male: 80 %

What is the age of people who have Splenic abscess when taking Isoniazid? *

What are other drugs people take besides Isoniazid? *

Pyrazinamide: 7 people, 43.75%
Rifampin: 3 people, 18.75%
Humira: 3 people, 18.75%
Ethambutol Hydrochloride: 3 people, 18.75%
Fluconazole: 2 people, 12.50%
Omeprazole: 2 people, 12.50%
Vancomycin: 2 people, 12.50%
Furosemide: 2 people, 12.50%
Zidovudine: 1 person, 6.25%
Atenolol: 1 person, 6.25%

What are other side effects people have besides Splenic abscess? *

Paradoxical Drug Reaction: 8 people, 50.00%
Pyogenic Liver Abscess (liver abscess caused by bacteria): 7 people, 43.75%
Pleural Effusion (water on the lungs): 6 people, 37.50%
Pneumonia: 4 people, 25.00%
Fever: 4 people, 25.00%
Abdominal Pain Upper: 3 people, 18.75%
Disseminated Tuberculosis: 3 people, 18.75%
Lung Abscess (pus in lungs): 3 people, 18.75%
Weight Decreased: 2 people, 12.50%
Nocardia Infection (a bacterial infection that usually starts in the lungs. it may spread to other organ systems): 2 people, 12.50%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 3 people, 18.75%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 12.50%
Oral Disorder (mouth disease): 2 people, 12.50%
Gastritis (inflammation of stomach): 2 people, 12.50%
Disseminated Tuberculosis: 2 people, 12.50%
Acute Febrile Neutrophilic Dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender): 2 people, 12.50%
Spleen Tuberculosis: 1 person, 6.25%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.25%
Pleural Effusion (water on the lungs): 1 person, 6.25%
Hiv Infection: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Isoniazid and have Splenic abscess?

- Check whether Splenic abscess is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isoniazid:

Isoniazid (20,174 reports)

Browse all side effects of Isoniazid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Splenic abscess:

Splenic abscess (66 drugs)

Browse all the conditions that are associated with Splenic abscess:

Splenic abscess (169 conditions)

Related publications that referenced our studies

Ganguly, R. J., Abraham, R. R., Prasad, R., & Rao, B. C, "Hyperglycaemia induced by isoniazid preventive therapy", Journal of Family Medicine and Primary Care, 2018 Jan .
Ganguly, R. J., Abraham, R. R., Prasad, R., & Rao, B. C, "Hyperglycaemia induced by isoniazid preventive therapy", Journal of Family Medicine and Primary Care, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on isoniazid (the active ingredients of Isoniazid) and Isoniazid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.