Isoptin sr and Acute kidney failure - a phase IV clinical study of FDA data

Summary:

Acute kidney failure is reported as a side effect among people who take Isoptin sr (verapamil hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Essential hypertension.

The phase IV clinical study analyzes which people have Acute kidney failure when taking Isoptin sr. It is created by eHealthMe based on reports of 825 people who have side effects when taking Isoptin sr from the FDA, and is updated regularly.

What is Isoptin sr?

Isoptin sr has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 850 Isoptin sr users. Check the latest studies of Isoptin sr.

What is Acute kidney failure?

Acute kidney failure is found to be associated with 2,835 drugs and 4,500 conditions by eHealthMe. Check the latest studies of Acute kidney failure.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

825 people reported to have side effects when taking Isoptin sr.
Among them, 39 people (4.73%) have Acute kidney failure.

Could Isoptin sr cause Acute kidney failure?

Among these 39 people:

How long have people been on Isoptin sr when they have Acute kidney failure? *

What is the gender of people who have Acute kidney failure when taking Isoptin sr? *

female: 61.29 %
male: 38.71 %

What is the age of people who have Acute kidney failure when taking Isoptin sr? *

What are other drugs people take besides Isoptin sr? *

What are other side effects people have besides Acute kidney failure? *

Hypotension (abnormally low blood pressure): 7 people, 17.95%
Hyperkalemia (damage to or disease of the kidney): 6 people, 15.38%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 6 people, 15.38%
Bradycardia (abnormally slow heart action): 5 people, 12.82%
Fall: 5 people, 12.82%
Malaise (a feeling of general discomfort or uneasiness): 5 people, 12.82%
Dehydration (dryness resulting from the removal of water): 5 people, 12.82%
Hypokalemia (low potassium): 5 people, 12.82%
Cardiac Failure: 5 people, 12.82%
Fainting (loss of consciousness and postural tone): 4 people, 10.26%

What are the existing conditions these people have? *

Essential Hypertension (primary hypertension): 4 people, 10.26%
Diabetes: 2 people, 5.13%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 5.13%
Suicide Attempt: 1 person, 2.56%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 2.56%
Pain: 1 person, 2.56%
Osteoporosis (bones weak and more likely to break): 1 person, 2.56%
Osteolysis (dissolution of bone): 1 person, 2.56%
Ischaemic Cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease): 1 person, 2.56%
Gout (uric acid crystals building up in the body): 1 person, 2.56%

* Approximation only. Some reports may have incomplete information.

Do you take Isoptin sr and have Acute kidney failure?

- Check whether Acute kidney failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isoptin sr:

Isoptin sr (850 reports)

Browse all side effects of Isoptin sr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute kidney failure:

Acute kidney failure (2,835 drugs)

Browse all the conditions that are associated with Acute kidney failure:

Acute kidney failure (4,500 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on verapamil hydrochloride (the active ingredients of Isoptin sr) and Isoptin sr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.