Isoptin sr and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Isoptin sr (verapamil hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Isoptin, and have Lung neoplasm malignant.

The phase IV clinical study analyzes which people have Constipation when taking Isoptin sr. It is created by eHealthMe based on reports of 825 people who have side effects when taking Isoptin sr from the FDA, and is updated regularly.

What is Isoptin sr?

Isoptin sr has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 850 Isoptin sr users. Check the latest studies of Isoptin sr.

What is Constipation?

Constipation is found to be associated with 3,004 drugs and 4,618 conditions by eHealthMe. Check the latest studies of Constipation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

825 people reported to have side effects when taking Isoptin sr.
Among them, 15 people (1.82%) have Constipation.

Among these 15 people:

How long have people been on Isoptin sr when they have Constipation? *

What is the gender of people who have Constipation when taking Isoptin sr? *

female: 45.45 %
male: 54.55 %

What is the age of people who have Constipation when taking Isoptin sr? *

What are other drugs people take besides Isoptin sr? *

What are other side effects people have besides Constipation? *

Dizziness: 7 people, 46.67%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 4 people, 26.67%
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 4 people, 26.67%
Hypokalemia (low potassium): 3 people, 20.00%
Drug Administration Error: 3 people, 20.00%
Drug Ineffective: 3 people, 20.00%
Vision Blurred: 3 people, 20.00%
Oedema (fluid collection in tissue): 2 people, 13.33%
Insomnia (sleeplessness): 2 people, 13.33%
Pressure Ulcer: 2 people, 13.33%

What are the existing conditions these people have? *

Parkinson's Disease: 2 people, 13.33%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 13.33%
Hepatitis B: 1 person, 6.67%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 6.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 6.67%
Arrhythmias (irregular heartbeat): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Isoptin sr and have Constipation?

- Check whether Constipation is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isoptin sr:

Isoptin sr (850 reports)

Constipation treatments and more:

Constipation (337,880 reports)

Browse all side effects of Isoptin sr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Constipation (3,004 drugs)

Browse all the conditions that are associated with Constipation:

Constipation (4,618 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on verapamil hydrochloride (the active ingredients of Isoptin sr) and Isoptin sr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.