Norco and Drooling - a phase IV clinical study of FDA data

Summary:

Drooling is reported as a side effect among people who take Norco (acetaminophen; hydrocodone bitartrate), especially for people who are female, 60+ old, also take Nexium, and have Adenocarcinoma pancreas.

The phase IV clinical study analyzes which people have Drooling when taking Norco. It is created by eHealthMe based on reports of 71,619 people who have side effects when taking Norco from the FDA, and is updated regularly.

What is Norco?

Norco has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 74,063 Norco users. Check the latest studies of Norco.

What is Drooling?

Drooling (drop saliva uncontrollably from the mouth) is found to be associated with 497 drugs and 941 conditions by eHealthMe. Check the latest studies of Drooling.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

71,619 people reported to have side effects when taking Norco.
Among them, 26 people (0.04%) have Drooling.

Among these 26 people:

What is the gender of people who have Drooling when taking Norco? *

female: 60 %
male: 40 %

What is the age of people who have Drooling when taking Norco? *

What are other drugs people take besides Norco? *

What are other side effects people have besides Drooling? *

Dyskinesia (abnormality or impairment of voluntary movement): 9 people, 34.62%
Weakness: 9 people, 34.62%
Speech Impairment (Adult) (inability to speak (adult)): 8 people, 30.77%
Dyspnea (difficult or laboured breathing): 8 people, 30.77%
Fatigue (feeling of tiredness): 8 people, 30.77%
Muscle Contractions Involuntary (uncontrolled muscle contraction): 7 people, 26.92%
Weight Decreased: 6 people, 23.08%
Insomnia (sleeplessness): 6 people, 23.08%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 6 people, 23.08%
Speech Disorder: 6 people, 23.08%

What are the existing conditions these people have? *

Adenocarcinoma Pancreas (cancer of pancreas): 5 people, 19.23%
Bipolar Disorder (mood disorder): 3 people, 11.54%
Nausea (feeling of having an urge to vomit): 3 people, 11.54%
Pancreatic Carcinoma (pancreatic cancer): 2 people, 7.69%
Gastrointestinal Motility Disorder (abnormal intestinal contractions): 2 people, 7.69%
Lung Cancer - Non-Small Cell (lung cancer): 1 person, 3.85%
Bone Pain: 1 person, 3.85%
Breast Cancer Metastatic: 1 person, 3.85%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 3.85%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Norco and have Drooling?

- Check whether Drooling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Norco:

Norco (74,063 reports)

Drooling treatments and more:

Drooling (8,115 reports)

How severe was Drooling and when was it recovered:

Drooling in Norco

Expand to all the drugs that have ingredients of acetaminophen; hydrocodone bitartrate:

Drooling and drugs with ingredients of acetaminophen; hydrocodone bitartrate (83 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Norco:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drooling:

Drooling (497 drugs)

Browse all the conditions that are associated with Drooling:

Drooling (941 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate (the active ingredients of Norco) and Norco (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.