Isoptin and Heart palpitations - a phase IV clinical study of FDA data

Summary:

Heart palpitations is reported as a side effect among people who take Isoptin (verapamil hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zyloprim, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Heart palpitations when taking Isoptin. It is created by eHealthMe based on reports of 5,465 people who have side effects when taking Isoptin from the FDA, and is updated regularly.

What is Isoptin?

Isoptin has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,539 Isoptin users. Check the latest studies of Isoptin.

What is Heart palpitations?

Heart palpitations (feelings or sensations that your heart is pounding or racing) is found to be associated with 2,444 drugs and 3,635 conditions by eHealthMe. Check the latest studies of Heart palpitations.



On Jul, 13, 2026

5,465 people reported to have side effects when taking Isoptin.
Among them, 92 people (1.68%) have Heart palpitations.

Could Isoptin cause Heart palpitations?

Among these 92 people:

How long have people been on Isoptin when they have Heart palpitations? *

  • < 1 month: 78.57 %
  • 1 - 6 months: 7.14 %
  • 6 - 12 months: 7.14 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 7.14 %

What is the gender of people who have Heart palpitations when taking Isoptin? *

  • female: 74.39 %
  • male: 25.61 %

What is the age of people who have Heart palpitations when taking Isoptin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.9 %
  • 20-29: 0.0 %
  • 30-39: 5.8 %
  • 40-49: 7.25 %
  • 50-59: 14.49 %
  • 60+: 69.57 %

What are other drugs people take besides Isoptin? *

  1. Zyloprim: 8 people, 8.70%
  2. Digoxin: 7 people, 7.61%
  3. Lipitor: 6 people, 6.52%
  4. Tylenol: 6 people, 6.52%
  5. Maxzide: 5 people, 5.43%
  6. Celebrex: 5 people, 5.43%
  7. Lanoxin: 5 people, 5.43%
  8. Vitamin B12: 5 people, 5.43%
  9. Dyazide: 4 people, 4.35%
  10. Premarin: 4 people, 4.35%

What are other side effects people have besides Heart palpitations? *

  1. Malaise (a feeling of general discomfort or uneasiness): 18 people, 19.57%
  2. Dizziness: 16 people, 17.39%
  3. Dyspnea (difficult or laboured breathing): 16 people, 17.39%
  4. Headache (pain in head): 16 people, 17.39%
  5. Weakness: 12 people, 13.04%
  6. Fatigue (feeling of tiredness): 11 people, 11.96%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 10 people, 10.87%
  8. Drug Ineffective: 10 people, 10.87%
  9. Arrhythmias (irregular heartbeat): 10 people, 10.87%
  10. Asthma: 9 people, 9.78%

What are the existing conditions these people have? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 7.61%
  2. Asthma: 6 people, 6.52%
  3. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 6.52%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 5.43%
  5. Osteoporosis (bones weak and more likely to break): 3 people, 3.26%
  6. Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 3 people, 3.26%
  7. Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 3.26%
  8. Depression: 3 people, 3.26%
  9. Migraine (headache): 2 people, 2.17%
  10. Arrhythmias (irregular heartbeat): 2 people, 2.17%

* Approximation only. Some reports may have incomplete information.

Do you take Isoptin and have Heart palpitations?

- Check whether Heart palpitations is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isoptin:

Heart palpitations treatments and more:

How severe was Heart palpitations and when was it recovered:

Expand to all the drugs that have ingredients of verapamil hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isoptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart palpitations:

Browse all the conditions that are associated with Heart palpitations:


How the study uses the data?

The study uses data from the FDA. It is based on verapamil hydrochloride (the active ingredients of Isoptin) and Isoptin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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