Isosorbide dinitrate and Liver function test abnormal - a phase IV clinical study of FDA data

Summary:

Liver function test abnormal is reported as a side effect among people who take Isosorbide dinitrate (isosorbide dinitrate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Spiriva, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Liver function test abnormal when taking Isosorbide dinitrate. It is created by eHealthMe based on reports of 13,073 people who have side effects when taking Isosorbide dinitrate from the FDA, and is updated regularly.

What is Isosorbide dinitrate?

Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.

What is Liver function test abnormal?

Liver function test abnormal is found to be associated with 1,497 drugs and 1,963 conditions by eHealthMe. Check the latest studies of Liver function test abnormal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

13,073 people reported to have side effects when taking Isosorbide dinitrate.
Among them, 44 people (0.34%) have Liver function test abnormal.

Could Isosorbide dinitrate cause Liver function test abnormal?

Among these 44 people:

How long have people been on Isosorbide dinitrate when they have Liver function test abnormal? *

What is the gender of people who have Liver function test abnormal when taking Isosorbide dinitrate? *

female: 63.41 %
male: 36.59 %

What is the age of people who have Liver function test abnormal when taking Isosorbide dinitrate? *

What are other drugs people take besides Isosorbide dinitrate? *

What are other side effects people have besides Liver function test abnormal? *

Acute Kidney Failure: 10 people, 22.73%
Aspartate Aminotransferase Increased: 9 people, 20.45%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 20.45%
Sepsis (a severe blood infection that can lead to organ failure and death): 8 people, 18.18%
Fluid Overload (too much fluid in the blood): 8 people, 18.18%
Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 8 people, 18.18%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 8 people, 18.18%
Cardiac Failure Congestive: 8 people, 18.18%
Pleural Effusion (water on the lungs): 8 people, 18.18%
Pneumonia: 8 people, 18.18%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 11.36%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 9.09%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 6.82%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 4.55%
Fungal Infection: 2 people, 4.55%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 2.27%
High Blood Cholesterol: 1 person, 2.27%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 2.27%
Cardiac Failure: 1 person, 2.27%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 2.27%

* Approximation only. Some reports may have incomplete information.

Do you take Isosorbide dinitrate and have Liver function test abnormal?

- Check whether Liver function test abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Isosorbide dinitrate:

Isosorbide dinitrate (13,180 reports)

Browse all side effects of Isosorbide dinitrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Liver function test abnormal:

Liver function test abnormal (1,497 drugs)

Browse all the conditions that are associated with Liver function test abnormal:

Liver function test abnormal (1,963 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on isosorbide dinitrate (the active ingredients of Isosorbide dinitrate) and Isosorbide dinitrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.