Ispaghula and Acute kidney failure - a phase IV clinical study of FDA data

Summary:

Acute kidney failure is reported as a side effect among people who take Ispaghula (blond psyllium), especially for people who are female, 40-49 old, also take Furosemide, and have Weight loss.

The phase IV clinical study analyzes which people have Acute kidney failure when taking Ispaghula. It is created by eHealthMe based on reports of 735 people who have side effects when taking Ispaghula from the FDA, and is updated regularly.

What is Ispaghula?

Ispaghula has active ingredients of blond psyllium. eHealthMe is studying from 737 Ispaghula users. Check the latest studies of Ispaghula.

What is Acute kidney failure?

Acute kidney failure is found to be associated with 2,835 drugs and 4,500 conditions by eHealthMe. Check the latest studies of Acute kidney failure.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

735 people reported to have side effects when taking Ispaghula.
Among them, 45 people (6.12%) have Acute kidney failure.

Could Ispaghula cause Acute kidney failure?

Among these 45 people:

What is the gender of people who have Acute kidney failure when taking Ispaghula? *

female: 71.43 %
male: 28.57 %

What is the age of people who have Acute kidney failure when taking Ispaghula? *

What are other drugs people take besides Ispaghula? *

Furosemide: 40 people, 88.89%
Vesicare: 37 people, 82.22%
Irbesartan: 37 people, 82.22%
Spironolactone: 37 people, 82.22%
Atenolol: 37 people, 82.22%
Trimethoprim: 37 people, 82.22%
Isosorbide Mononitrate: 37 people, 82.22%
Omeprazole: 35 people, 77.78%
Aspirin: 34 people, 75.56%
Lisinopril: 32 people, 71.11%

What are other side effects people have besides Acute kidney failure? *

Weight Increased: 37 people, 82.22%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 37 people, 82.22%
Fear Of Eating: 37 people, 82.22%
High Blood Pressure: 37 people, 82.22%
Fever: 36 people, 80.00%
Indigestion: 34 people, 75.56%
Dehydration (dryness resulting from the removal of water): 33 people, 73.33%
Rectal Haemorrhage (bleeding from anus): 32 people, 71.11%
Back Pain: 32 people, 71.11%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 31 people, 68.89%

What are the existing conditions these people have? *

Weight Loss: 35 people, 77.78%
Cardiac Disorder: 26 people, 57.78%
Urinary Tract Infection: 16 people, 35.56%
Bladder Disorder: 16 people, 35.56%
Muscle Spasms (muscle contraction): 10 people, 22.22%
Weight Decreased: 7 people, 15.56%
Diabetes: 3 people, 6.67%
Depression: 2 people, 4.44%
Post Procedural Discharge: 1 person, 2.22%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 2.22%

* Approximation only. Some reports may have incomplete information.

Do you take Ispaghula and have Acute kidney failure?

- Check whether Acute kidney failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ispaghula:

Ispaghula (737 reports)

Browse all side effects of Ispaghula:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute kidney failure:

Acute kidney failure (2,835 drugs)

Browse all the conditions that are associated with Acute kidney failure:

Acute kidney failure (4,500 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on blond psyllium (the active ingredients of Ispaghula) and Ispaghula (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.