Istodax and Malaise - a phase IV clinical study of FDA data

Summary:

Malaise is reported as a side effect among people who take Istodax (romidepsin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Diflucan, and have Peripheral t-cell lymphoma unspecified.

The phase IV clinical study analyzes which people have Malaise when taking Istodax. It is created by eHealthMe based on reports of 1,053 people who have side effects when taking Istodax from the FDA, and is updated regularly.

What is Istodax?

Istodax has active ingredients of romidepsin. eHealthMe is studying from 1,054 Istodax users. Check the latest studies of Istodax.

What is Malaise?

Malaise (a feeling of general discomfort or uneasiness) is found to be associated with 3,497 drugs and 5,122 conditions by eHealthMe. Check the latest studies of Malaise.

On Jul, 31, 2026

1,053 people reported to have side effects when taking Istodax.
Among them, 26 people (2.47%) have Malaise.

Among these 26 people:

How long have people been on Istodax when they have Malaise? *

What is the gender of people who have Malaise when taking Istodax? *

female: 33.33 %
male: 66.67 %

What is the age of people who have Malaise when taking Istodax? *

What are other drugs people take besides Istodax? *

What are other side effects people have besides Malaise? *

Nausea (feeling of having an urge to vomit): 15 people, 57.69%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 10 people, 38.46%
Thrombocytopenia (decrease of platelets in blood): 9 people, 34.62%
Nausea And Vomiting: 7 people, 26.92%
Anaemia (lack of blood): 7 people, 26.92%
Fever: 7 people, 26.92%
Constipation: 7 people, 26.92%
Taste - Impaired: 6 people, 23.08%
White Blood Cell Count Decreased: 5 people, 19.23%
Liver Disorder (liver diseases): 5 people, 19.23%

What are the existing conditions these people have? *

Peripheral T-Cell Lymphoma Unspecified (peripheral t-cell cancer unspecified): 13 people, 50.00%
Hiv Infection: 3 people, 11.54%
Angioimmunoblastic T-Cell Lymphoma (mature t-cell cancer of the blood or lymph vessel): 3 people, 11.54%
Peripheral T-Cell Lymphoma Unspecified Recurrent (peripheral t-cell cancer unspecified recurrent): 1 person, 3.85%
Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 1 person, 3.85%
Lymphoma (cancer that begins in immune system cells): 1 person, 3.85%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 3.85%
Adverse Event: 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Istodax and have Malaise?

- Check whether Malaise is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Istodax:

Istodax (1,054 reports)

Malaise treatments and more:

Malaise (529,933 reports)

Browse all side effects of Istodax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Malaise:

Malaise (3,497 drugs)

Browse all the conditions that are associated with Malaise:

Malaise (5,122 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on romidepsin (the active ingredients of Istodax) and Istodax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.