Janumet and Tinnitus - a phase IV clinical study of FDA data

Summary:

Tinnitus is reported as a side effect among people who take Janumet (metformin hydrochloride; sitagliptin phosphate), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Januvia, and have High blood pressure.

The phase IV clinical study analyzes which people have Tinnitus when taking Janumet. It is created by eHealthMe based on reports of 24,406 people who have side effects when taking Janumet from the FDA, and is updated regularly.

What is Janumet?

Janumet has active ingredients of metformin hydrochloride; sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 25,023 Janumet users. Check the latest studies of Janumet.

What is Tinnitus?

Tinnitus (a ringing in the ears) is found to be associated with 1,669 drugs and 3,056 conditions by eHealthMe. Check the latest studies of Tinnitus.

On Apr, 11, 2026

24,406 people reported to have side effects when taking Janumet.
Among them, 64 people (0.26%) have Tinnitus.

Among these 64 people:

How long have people been on Janumet when they have Tinnitus? *

What is the gender of people who have Tinnitus when taking Janumet? *

female: 71.43 %
male: 28.57 %

What is the age of people who have Tinnitus when taking Janumet? *

What are other drugs people take besides Janumet? *

Januvia: 16 people, 25.00%
Metformin Hydrochloride: 15 people, 23.44%
Morphine: 14 people, 21.88%
Xolair: 13 people, 20.31%
Neoral: 13 people, 20.31%
Cyclosporine: 13 people, 20.31%
Lyrica: 11 people, 17.19%
Diclofenac: 10 people, 15.62%
Norvir: 10 people, 15.62%
Sinequan: 10 people, 15.62%

What are other side effects people have besides Tinnitus? *

Dizziness: 33 people, 51.56%
Weight Decreased: 27 people, 42.19%
Weakness: 26 people, 40.62%
Abdominal Pain: 26 people, 40.62%
Memory Loss: 25 people, 39.06%
Insomnia (sleeplessness): 24 people, 37.50%
Back Pain: 24 people, 37.50%
Productive Cough: 24 people, 37.50%
Pain In Extremity: 23 people, 35.94%
Joint Pain: 23 people, 35.94%

What are the existing conditions these people have? *

High Blood Pressure: 16 people, 25.00%
Psoriasis (immune-mediated disease that affects the skin): 13 people, 20.31%
Immunodeficiency: 13 people, 20.31%
Blood Glucose Abnormal: 12 people, 18.75%
Breast Cancer: 10 people, 15.62%
Pain: 9 people, 14.06%
Blood Pressure Abnormal: 8 people, 12.50%
Renal Cell Carcinoma (a kidney cancer): 7 people, 10.94%
Helicobacter Infection (helicobacter pylori (h. pylori) infects stomach): 5 people, 7.81%
Pericarditis (inflammation of the pericardium): 5 people, 7.81%

* Approximation only. Some reports may have incomplete information.

Do you take Janumet and have Tinnitus?

- Check whether Tinnitus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Janumet:

Janumet (25,023 reports)

Tinnitus treatments and more:

Tinnitus (58,552 reports)

How severe was Tinnitus and when was it recovered:

Tinnitus in Janumet

Expand to all the drugs that have ingredients of metformin hydrochloride; sitagliptin phosphate:

Tinnitus and drugs with ingredients of metformin hydrochloride; sitagliptin phosphate (16 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Janumet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tinnitus:

Tinnitus (1,669 drugs)

Browse all the conditions that are associated with Tinnitus:

Tinnitus (3,056 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride; sitagliptin phosphate (the active ingredients of Janumet) and Janumet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.