Promethazine hydrochloride and Swallowing difficulty - a phase IV clinical study of FDA data

Summary:

Swallowing difficulty is reported as a side effect among people who take Promethazine hydrochloride (promethazine hydrochloride), especially for people who are female, 40-49 old, also take Prednisone, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Swallowing difficulty when taking Promethazine hydrochloride. It is created by eHealthMe based on reports of 2,575 people who have side effects when taking Promethazine hydrochloride from the FDA, and is updated regularly.

What is Promethazine hydrochloride?

Promethazine hydrochloride has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 2,954 Promethazine hydrochloride users. Check the latest studies of Promethazine hydrochloride.

What is Swallowing difficulty?

Swallowing difficulty is found to be associated with 2,403 drugs and 3,350 conditions by eHealthMe. Check the latest studies of Swallowing difficulty.

On Jul, 05, 2026

2,575 people reported to have side effects when taking Promethazine hydrochloride.
Among them, 27 people (1.05%) have Swallowing difficulty.

Could Promethazine hydrochloride cause Swallowing difficulty?

Among these 27 people:

What is the gender of people who have Swallowing difficulty when taking Promethazine hydrochloride? *

female: 76.92 %
male: 23.08 %

What is the age of people who have Swallowing difficulty when taking Promethazine hydrochloride? *

What are other drugs people take besides Promethazine hydrochloride? *

Prednisone: 10 people, 37.04%
Acetaminophen: 9 people, 33.33%
Protonix: 8 people, 29.63%
Gabapentin: 8 people, 29.63%
Omeprazole: 8 people, 29.63%
Dilaudid: 7 people, 25.93%
Tylenol: 7 people, 25.93%
Hydroxyzine Hydrochloride: 7 people, 25.93%
Zofran: 7 people, 25.93%
Ativan: 6 people, 22.22%

What are other side effects people have besides Swallowing difficulty? *

Rashes (redness): 11 people, 40.74%
Pain: 10 people, 37.04%
Pain In Extremity: 10 people, 37.04%
Back Pain: 10 people, 37.04%
Dyspnea (difficult or laboured breathing): 10 people, 37.04%
Stress And Anxiety: 10 people, 37.04%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 33.33%
Dizziness: 9 people, 33.33%
Diarrhea: 8 people, 29.63%
Depression: 8 people, 29.63%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 22.22%
Stress And Anxiety: 3 people, 11.11%
Dehydration (dryness resulting from the removal of water): 3 people, 11.11%
Immunodeficiency Common Variable: 3 people, 11.11%
Multiple Myeloma (cancer of the plasma cells): 3 people, 11.11%
Breast Cancer Metastatic: 2 people, 7.41%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 2 people, 7.41%
Metastases To Bone (cancer spreads to bone): 2 people, 7.41%
Colon Cancer: 1 person, 3.70%
Depression: 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Promethazine hydrochloride and have Swallowing difficulty?

- Check whether Swallowing difficulty is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Promethazine hydrochloride:

Promethazine hydrochloride (2,954 reports)

Browse all side effects of Promethazine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Swallowing difficulty:

Swallowing difficulty (2,403 drugs)

Browse all the conditions that are associated with Swallowing difficulty:

Swallowing difficulty (3,350 conditions)

Related publications that referenced our studies

Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on promethazine hydrochloride (the active ingredients of Promethazine hydrochloride) and Promethazine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.