Kadcyla and Abdominal distension - a phase IV clinical study of FDA data

Summary:

Abdominal distension is reported as a side effect among people who take Kadcyla (ado-trastuzumab emtansine), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Herceptin, and have Breast cancer metastatic.

The phase IV clinical study analyzes which people have Abdominal distension when taking Kadcyla. It is created by eHealthMe based on reports of 5,798 people who have side effects when taking Kadcyla from the FDA, and is updated regularly.

What is Kadcyla?

Kadcyla has active ingredients of ado-trastuzumab emtansine. eHealthMe is studying from 5,813 Kadcyla users. Check the latest studies of Kadcyla.

What is Abdominal distension?

Abdominal distension is found to be associated with 2,575 drugs and 3,639 conditions by eHealthMe. Check the latest studies of Abdominal distension.

On Jul, 14, 2026

5,798 people reported to have side effects when taking Kadcyla.
Among them, 27 people (0.47%) have Abdominal distension.

Could Kadcyla cause Abdominal distension?

Among these 27 people:

How long have people been on Kadcyla when they have Abdominal distension? *

What is the gender of people who have Abdominal distension when taking Kadcyla? *

female: 100 %
male: 0.0 %

What is the age of people who have Abdominal distension when taking Kadcyla? *

What are other drugs people take besides Kadcyla? *

Herceptin: 16 people, 59.26%
Perjeta: 12 people, 44.44%
Xeloda: 9 people, 33.33%
Zofran: 6 people, 22.22%
Diphenhydramine Hydrochloride: 6 people, 22.22%
Dexamethasone: 6 people, 22.22%
Ciprofloxacin: 6 people, 22.22%
Capecitabine: 6 people, 22.22%
Ranitidine Hydrochloride: 5 people, 18.52%
Emend: 5 people, 18.52%

What are other side effects people have besides Abdominal distension? *

Weight Decreased: 9 people, 33.33%
Dyspnea (difficult or laboured breathing): 8 people, 29.63%
Headache (pain in head): 8 people, 29.63%
Diarrhea: 8 people, 29.63%
Nausea (feeling of having an urge to vomit): 8 people, 29.63%
Nausea And Vomiting: 8 people, 29.63%
Thrombocytopenia (decrease of platelets in blood): 7 people, 25.93%
Fatigue (feeling of tiredness): 6 people, 22.22%
Oedema Peripheral (superficial swelling): 6 people, 22.22%
Stress And Anxiety: 5 people, 18.52%

What are the existing conditions these people have? *

Breast Cancer Metastatic: 12 people, 44.44%
Breast Cancer: 11 people, 40.74%
Pain: 5 people, 18.52%
Diarrhea: 5 people, 18.52%
Neoplasm Progression (growth of tumour): 2 people, 7.41%
Indigestion: 2 people, 7.41%
Stress And Anxiety: 1 person, 3.70%
Metastases To Central Nervous System (cancer spreads to central nervous system): 1 person, 3.70%
Insomnia (sleeplessness): 1 person, 3.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Kadcyla and have Abdominal distension?

- Check whether Abdominal distension is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Kadcyla:

Kadcyla (5,813 reports)

Browse all side effects of Kadcyla:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Abdominal distension:

Abdominal distension (2,575 drugs)

Browse all the conditions that are associated with Abdominal distension:

Abdominal distension (3,639 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ado-trastuzumab emtansine (the active ingredients of Kadcyla) and Kadcyla (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.