Keflex and Cachexia - a phase IV clinical study of FDA data

Summary:

Cachexia is reported as a side effect among people who take Keflex (cephalexin), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Zometa, and have Neoplasm malignant.

The phase IV clinical study analyzes which people have Cachexia when taking Keflex. It is created by eHealthMe based on reports of 14,902 people who have side effects when taking Keflex from the FDA, and is updated regularly.

What is Keflex?

Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,842 Keflex users. Check the latest studies of Keflex.

What is Cachexia?

Cachexia (loss of weight) is found to be associated with 715 drugs and 1,194 conditions by eHealthMe. Check the latest studies of Cachexia.



On Dec, 22, 2025

14,902 people reported to have side effects when taking Keflex.
Among them, 38 people (0.25%) have Cachexia.

Could Keflex cause Cachexia?

Among these 38 people:

How long have people been on Keflex when they have Cachexia? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Cachexia when taking Keflex? *

  • female: 78.95 %
  • male: 21.05 %

What is the age of people who have Cachexia when taking Keflex? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 2.94 %
  • 40-49: 8.82 %
  • 50-59: 61.76 %
  • 60+: 26.47 %

What are other drugs people take besides Keflex? *

  1. Zometa: 30 people, 78.95%
  2. Decadron: 24 people, 63.16%
  3. Paxil: 23 people, 60.53%
  4. Xanax: 22 people, 57.89%
  5. Nystatin: 20 people, 52.63%
  6. Aromasin: 20 people, 52.63%
  7. Vicodin: 19 people, 50.00%
  8. Versed: 19 people, 50.00%
  9. Fentanyl: 18 people, 47.37%
  10. Gemzar: 17 people, 44.74%

What are other side effects people have besides Cachexia? *

  1. Anaemia (lack of blood): 30 people, 78.95%
  2. Pain: 30 people, 78.95%
  3. Fatigue (feeling of tiredness): 29 people, 76.32%
  4. Pain In Jaw: 29 people, 76.32%
  5. Weakness: 28 people, 73.68%
  6. Stress And Anxiety: 28 people, 73.68%
  7. Metastases To Bone (cancer spreads to bone): 26 people, 68.42%
  8. Osteomyelitis (infection of bone): 25 people, 65.79%
  9. Swallowing Difficulty: 25 people, 65.79%
  10. Osteonecrosis Of Jaw (death of bone of jaw): 25 people, 65.79%

What are the existing conditions these people have? *

  1. Neoplasm Malignant (cancer tumour): 5 people, 13.16%
  2. Breast Cancer Metastatic: 4 people, 10.53%
  3. Breast Cancer: 4 people, 10.53%
  4. Cardiac Failure Congestive: 2 people, 5.26%
  5. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 1 person, 2.63%
  6. Lung Cancer Metastatic (lung cancer spreads to other parts): 1 person, 2.63%
  7. Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 1 person, 2.63%
  8. Heart Rate Irregular: 1 person, 2.63%
  9. Enlarged Heart: 1 person, 2.63%
  10. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Keflex and have Cachexia?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Keflex:

Cachexia treatments and more:

How severe was Cachexia and when was it recovered:

Expand to all the drugs that have ingredients of cephalexin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Keflex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cachexia:

Browse all the conditions that are associated with Cachexia:

Drugs similar to Keflex and Cachexia :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cephalexin (the active ingredients of Keflex) and Keflex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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