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Keflex and Chapped lips - a phase IV clinical study of FDA data

Summary:

Chapped lips is reported as a side effect among people who take Keflex (cephalexin), especially for people who are male, 10-19 old, have been taking the drug for < 1 month also take Accutane, and have Acne.

The phase IV clinical study analyzes which people have Chapped lips when taking Keflex. It is created by eHealthMe based on reports of 14,902 people who have side effects when taking Keflex from the FDA, and is updated regularly.

What is Keflex?

Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,844 Keflex users. Check the latest studies of Keflex.

What is Chapped lips?

Chapped lips (cracking, fissuring, and peeling of the skin f lip) is found to be associated with 428 drugs and 870 conditions by eHealthMe. Check the latest studies of Chapped lips.

On Jul, 09, 2026

14,902 people reported to have side effects when taking Keflex.
Among them, 28 people (0.19%) have Chapped lips.

Could Keflex cause Chapped lips?

Among these 28 people:

How long have people been on Keflex when they have Chapped lips? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Chapped lips when taking Keflex? *

  • female: 10.71 %
  • male: 89.29 %

What is the age of people who have Chapped lips when taking Keflex? *

  • 0-1: 0.0 %
  • 2-9: 3.7 %
  • 10-19: 88.89 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 3.7 %
  • 60+: 3.7 %

What are other drugs people take besides Keflex? *

  1. Accutane: 25 people, 89.29%
  2. Retin-A: 9 people, 32.14%
  3. Benzamycin: 5 people, 17.86%
  4. Lidex: 3 people, 10.71%
  5. Allegra: 3 people, 10.71%
  6. Aclovate: 3 people, 10.71%
  7. Ventolin Hfa: 1 person, 3.57%
  8. Phenergan: 1 person, 3.57%

What are other side effects people have besides Chapped lips? *

  1. Lip Dry: 18 people, 64.29%
  2. Joint Pain: 17 people, 60.71%
  3. Muscle Aches (muscle pain): 17 people, 60.71%
  4. Dry Skin: 16 people, 57.14%
  5. Inflammatory Bowel Disease: 16 people, 57.14%
  6. Depression: 15 people, 53.57%
  7. Nasal Dryness (dry nose): 15 people, 53.57%
  8. Abdominal Pain: 13 people, 46.43%
  9. Colitis (inflammation of colon): 13 people, 46.43%
  10. Dehydration (dryness resulting from the removal of water): 13 people, 46.43%

What are the existing conditions these people have? *

  1. Acne (skin problems that cause pimples): 13 people, 46.43%
  2. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 12 people, 42.86%
  3. Pharyngolaryngeal Pain: 1 person, 3.57%
  4. Ovarian Cancer (cancer of ovary): 1 person, 3.57%
  5. Hordeolum (small collection of pus (abscess) on the eyelid): 1 person, 3.57%
  6. Dyspnea (difficult or laboured breathing): 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Keflex and have Chapped lips?

- Check whether Chapped lips is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Keflex:

Chapped lips treatments and more:

How severe was Chapped lips and when was it recovered:

Expand to all the drugs that have ingredients of cephalexin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Keflex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chapped lips:

Browse all the conditions that are associated with Chapped lips:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on cephalexin (the active ingredients of Keflex) and Keflex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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