Keflex and Emphysema - a phase IV clinical study of FDA data
Summary:
Emphysema is found among people who take Keflex, especially for people who are female, 50-59 old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Keflex and have Emphysema. It is created by eHealthMe based on reports of 13,830 people who have side effects when taking Keflex from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
13,830 people reported to have side effects when taking Keflex.
Among them, 86 people (0.62%) have Emphysema.
What is Keflex?
Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 14,749 Keflex users for its effectiveness, alternative drugs and more.
What is Emphysema?
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs) is found to be associated with 1,850 drugs and 1,088 conditions by eHealthMe.
Number of Keflex and Emphysema reports submitted per year:

Time on Keflex when people have Emphysema *:
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Emphysema when taking Keflex *:
- female: 66.28 %
- male: 33.72 %
Age of people who have Emphysema when taking Keflex *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 1.52 %
- 20-29: 1.52 %
- 30-39: 0.0 %
- 40-49: 4.55 %
- 50-59: 63.64 %
- 60+: 28.79 %
Common drugs people take besides Keflex *:
- Zometa: 58 people, 67.44%
- Lovenox: 38 people, 44.19%
- Lortab: 32 people, 37.21%
- Flexeril: 32 people, 37.21%
- Neurontin: 31 people, 36.05%
- Amoxicillin: 29 people, 33.72%
- Lasix: 28 people, 32.56%
- Zofran: 28 people, 32.56%
- Decadron: 27 people, 31.40%
- Lisinopril: 26 people, 30.23%
Common side effects people have besides Emphysema *:
- Breathing Difficulty: 63 people, 73.26%
- Back Pain: 61 people, 70.93%
- Pain: 61 people, 70.93%
- Osteonecrosis Of Jaw (death of bone of jaw): 58 people, 67.44%
- Stress And Anxiety: 57 people, 66.28%
- Anaemia (lack of blood): 56 people, 65.12%
- Pneumonia: 55 people, 63.95%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 53 people, 61.63%
- Injury: 49 people, 56.98%
- Atelectasis (partial or complete collapse of the lung): 48 people, 55.81%
Common conditions people have *:
- Neoplasm Malignant (cancer tumour): 13 people, 15.12%
- Multiple Myeloma (cancer of the plasma cells): 10 people, 11.63%
- Bone Disorder: 8 people, 9.30%
- Depression: 7 people, 8.14%
- Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 6 people, 6.98%
- Back Pain: 6 people, 6.98%
- Constipation: 3 people, 3.49%
- High Blood Pressure: 3 people, 3.49%
- Pain: 3 people, 3.49%
- Chest Pain: 3 people, 3.49%
* Approximation only. Some reports may have incomplete information.
Do you take Keflex and have Emphysema?
Check whether Emphysema is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .
Related studies
How severe was Emphysema and when was it recovered:
Expand to all the drugs that have ingredients of cephalexin:
- Emphysema and drugs with ingredients of cephalexin (142 reports)
Alternative drugs to, pros and cons of Keflex:
- Keflex (14,749 reports)
Common Keflex side effects:
- Pain: 1,593 reports
- Fatigue (feeling of tiredness): 1,354 reports
- Breathing difficulty: 1,314 reports
- Stress and anxiety: 1,297 reports
- Rashes (redness): 1,192 reports
- Diarrhea: 1,066 reports
Browse all side effects of Keflex:
a b c d e f g h i j k l m n o p q r s t u v w x y zEmphysema treatments and more:
- Emphysema (27,509 reports)
COVID vaccines that are related to Emphysema:
- Emphysema in Moderna COVID Vaccine
- Emphysema in Pfizer BioNTech Covid Vaccine
- Emphysema in Johnson and Johnson Covid Vaccine
Common drugs associated with Emphysema:
- Prednisone: 1,628 reports
- Spiriva: 1,247 reports
- Aspirin: 909 reports
- Fosamax: 860 reports
- Symbicort: 802 reports
- Zometa: 764 reports
- Methotrexate: 738 reports
- Albuterol: 729 reports
- Lasix: 586 reports
- Humira: 530 reports
All the drugs that are associated with Emphysema:
- Emphysema (1,850 drugs)
Common conditions associated with Emphysema:
- Rheumatoid arthritis: 1,134 reports
- Osteoporosis: 1,021 reports
- Chronic obstructive pulmonary disease: 755 reports
- High blood pressure: 740 reports
- Asthma: 709 reports
All the conditions that are associated with Emphysema:
- Emphysema (1,088 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on cephalexin (the active ingredients of Keflex) and Keflex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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